Results 71 to 80 of about 33,534 (216)

2021–2023 Unrest and Geodetic Observations at Askja Volcano, Iceland

Geophysical Research Letters
Unrest began in July 2021 at Askja volcano in the Northern Volcanic Zone (NVZ) of Iceland. Its most recent eruption, in 1961, was predominantly effusive and produced ∼0.1 km3 lava field. The last plinian eruption at Askja occurred in 1875.
Michelle M. Parks, Freysteinn Sigmundsson, Vincent Drouin, Sigrún Hreinsdóttir, Andrew Hooper, Yilin Yang, Benedikt G. Ófeigsson, Erik Sturkell, Ásta R. Hjartardóttir, Ronni Grapenthin, Halldór Geirsson, Elisa Trasatti, Sara Barsotti, Rikke Pedersen, Páll Einarsson, Bergrún A. Óladóttir, Hildur M. Friðriksdóttir   +16 more
doaj   +1 more source

Geomagnetic anomalies observed at volcano Popocatepetl, Mexico [PDF]

Advances in Geosciences, 2008
Results of the ULF geomagnetic monitoring of the volcano Popocatepetl (Mexico) and their analysis are summarized and presented for the period 2003–2006.
A. Kotsarenko, V. Grimalsky, R. Pérez Enríquez, V. Yutsis, S. Koshevaya, J. A. López Cruz-Abeyro, C. Valdez-Gonzalez, R. A. Villegas Cerón   +7 more
doaj  

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

Advanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang, Jianhua Li, Huilu Zhang, Qi Qin, Yichen Huang, Xiaofan Tian, Chao Sun, Binbin Li, Zhengxin Wang, Xin Zhang   +9 more
wiley   +1 more source

Monitoring of fumarole discharge and CO2 soil degassing in the Azores: contribution to volcanic surveillance and public health risk assessment

Annals of Geophysics, 2005
Fluid geochemistry monitoring in the Azores involves the regular sampling and analysis of gas discharges from fumaroles and measurements of CO2 diffuse soil gas emissions.
C. Faria, M. Marcos, F. Viveiros, J. L. Gaspar, T. Ferreira, F. Sousa   +5 more
doaj   +1 more source

Copper‐Driven Epithelial Barrier Disruption: A Novel Mechanism of COPD Acute Exacerbations Mediated by the TNF‐α/ATP7A Axis

Advanced Science, EarlyView.
This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao, Yongzhe Hao, Ziqi Ding, Zhipeng Wang, Yujia Shi, Yanhua Huang, Chunjian Qi, Qian Zhang   +7 more
wiley   +1 more source

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

Advanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu, Miaozhan Zou, Yunshang Bai, Yang He, Zhihao Jin, Baozhi Yang, Jinjin Du, Pei Ouyang, Yuanyuan Cai, Yuheng Zhang, Bingying Du, Chengcheng Ge, Jian‐an Gong, Xiaoyu Li, Yuanyi Zheng, Jing Ding, Bo Peng, Yanxia Rao   +17 more
wiley   +1 more source

Near-real-time design of experiments for seismic monitoring of volcanoes

Seismica
Monitoring the seismic activity of volcanoes is crucial for hazard assessment and eruption forecasting. The layout of each seismic network determines the information content of recorded data about volcanic earthquakes, and experimental design methods ...
Dominik Strutz, Andrew Curtis
doaj   +1 more source

Neural networks and dynamical system techniques for volcanic tremor analysis

Annals of Geophysics, 1996
A volcano can be seen as a dynamical system, the number of state variables being its dimension N. The state is usually confined on a manifold with a lower dimension f, manifold which is characteristic of a persistent «structural configuration».
R. Carniel
doaj   +1 more source

UDP‐Glucose‐6‐Dehydrogenase Mediated O‐GlcNAcylation of Tight Junction Protein 1 Suppresses Metastasis in Renal Cell Carcinoma

Advanced Science, EarlyView.
Our research unveiled a regulatory paradigm wherein TRIM25 orchestrates the ubiquitin‐mediated degradation of UGDH. UGDH modulates the protein stability of TJP1 by regulating O‐GlcNAcylation levels, effectively impeding the metastasis of ccRCC. Our insights elevate UGDH to a pivotal biomarker and tumor suppressor, marking the first demonstration that ...
Xiaolin Chen, Yuhang Bao, Tao Liu, Jianhui Qiu, Yuanyuan Ma, Zedan Zhang, Chuandong Wang, Ruiyi Deng, Zheng Song, Tianyi He, Haode Liu, Jingcheng Zhou, Yizhou Wang, Kan Gong   +13 more
wiley   +1 more source