Results 81 to 90 of about 33,534 (216)

Preface

Annals of Geophysics, 2013
Mt. Vesuvius is one of the most hazardous volcanoes in the world, due to the highly populated surrounding area, where more than 800,000 people live. It experienced various regimes of eruptive activity, from effusive to Plinian.
Francesca Bianco, Stefano Caliro, Mario La Rocca, Umberto Tammaro   +3 more
doaj   +1 more source

Chiral Nanoparticles Suppress Inflammatory Infiltration to Promote Extracellular Matrix Remodeling for Ectopia Lentis Therapy

Advanced Science, EarlyView.
L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen, Yan Yang, Haihan Gao, Yan Liu, Xinyue Wang, Linghao Song, Ruohong Li, Ao Miao, Jie Xu, Zhennan Zhao, Dan Li, Shenjie Peng, Linzhao Li, Min Zhang, Yonghang Liu, Liren Wang, Tianhui Chen, Yongxiang Jiang   +17 more
wiley   +1 more source

3D Habitat Complexity and Coral Morphology Modulate Reef Fish Functional Structure in a Marine National Park

Ecology and Evolution
The ongoing degradation of coral reef habitats is widely acknowledged to have adverse effects on the abundance and diversity of reef fish populations, yet the direct effects on ecosystem functions remain uncertain. This study used a quantitative approach
Sofia B. Ferreira, John H. R. Burns, Atsuko Fukunaga, Lillian J. Tuttle Raz, Sheila A. McKenna, Kailea Annandale, Ryan J. Monello   +6 more
doaj   +1 more source

Potential laharic risks associated with the Millennium Eruption products of Tianchi volcano, NE China

Natural Hazards Research
Tianchi volcano has experienced continuous eruptions, including the Millennium Eruption (ME) event that produced a volcanic explosivity index of 6–7 in approximately 946 CE, which is among the most hazardous eruptions in human history.
Zhengquan Chen, Haiquan Wei, Yuan Wan, Bo Zhao, Xiaoxuan Li   +4 more
doaj   +1 more source

Could seismo-volcanic catalogs be improved or created using weakly supervised approaches with pre-trained systems? [PDF]

Natural Hazards and Earth System Sciences
Real-time monitoring of volcano-seismic signals is complex. Typically, automatic systems are built by learning from large seismic catalogs, where each instance has a label indicating its source mechanism.
M. Titos, M. Titos, C. Benítez, C. Benítez, L. D'Auria, M. Kowsari, J. M. Ibáñez, J. M. Ibáñez   +7 more
doaj   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease

Advanced Science, EarlyView.
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li, Hao Tang, Qin Yu, Yuyang Zhang, Binglu Shi, Ying Kong, Leiyu Xu, Jingjing Shao, Chenghong Hu, Lingyu She, Zhe Wang, Haiyi Chen, Aleksandr V. Samorodov, Gang Cao, Xia Zhao, Yi Wang   +15 more
wiley   +1 more source

Vision Transformers and CNNs for Microearthquake Recognition: Exploring Generalization Among Volcanoes

IEEE Access
Latin American populations face the risk of possible eruptions from approximately 300 active volcanoes in the region. Therefore, continuous volcanic monitoring is crucial for Early Warning Systems.
Fernando Lara, Ana Maria Zambrano, Roman A. Lara-Cueva, Felipe Grijalva   +3 more
doaj   +1 more source

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

Advanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu, Chong Wu, Shiyao Song, Li Ma, Shaoqing Huang, Yuting He, Qinghai Li, Yanzhou Chang, Dan Jiang, Yong Mei, Junchao Cai, Zhenshuang Du, Tianfeng Chen, Weiling He   +13 more
wiley   +1 more source

Astrocytic LMP2 Coordinates NF‐κB and TGF‐β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao, Rulan Ma, Zejing Lin, Huiying Zhao, Yuexian Liu, Yonghe Su, Xu Zhang, Xingyong Chen   +7 more
wiley   +1 more source