Results 31 to 40 of about 24,402 (251)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Tephra fallout hazard assessment for a hydrovolcanic eruptive scenario in Mayotte

Scientific Reports
The new submarine volcano Fani Maoré offshore Mayotte (Comoros archipelago) discovered in 2019 has raised the awareness of a possible future eruption in Petite-Terre island, located on the same 60 km-long volcanic chain.
Audrey Michaud-Dubuy, Jean-Christophe Komorowski, Tristan Lacombe, Lucia Gurioli   +3 more
doaj   +1 more source

Experimental Study on Long Short-term Memory Networks for Identifying P-wave Primary Phase

CT Lilun yu yingyong yanjiu
Identifying primary phases of seismic waveforms is a routine task in seismic data processing. Owing to the low efficiency of manual identification and the influence of human subjective factors, many methods for the automatic identification of the primary
Tianzhe WANG, Wanji ZHANG, Shanbo QI, Guoming JIANG   +3 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

RRS "Charles Darwin" Cruise 178, 14 Mar - 11 Apr 2006. 3D seismic acquisition over mud volcanoes in the Gulf of Cadiz and submarine landslides in the Eivissa Channel, western Mediterranean Sea [PDF]

, 2006
The major aims of Charles Darwin Cruise 178 were to obtain (i) 3D seismic imagery, video transects and swath bathymetry maps of mud volcanoes in the southern Gulf of Cadiz, (ii) video transects across suspected cold water coral reefs in the Alboran Sea ...
Berndt, C., Masson, D.G.
core  

First-Arrival Tomography for Mountain Tunnel Hazard Assessment Using Unmanned Aerial Vehicle Seismic Source and Enhanced by Supervirtual Interferometry

Remote Sensing
Preliminary tunnel surveys are essential for identifying geological hazards such as aquifers, faults, and karstic zones. While first-arrival tomography is effective for imaging shallow anomalies, traditional seismic sources face significant limitations ...
Jun Zhang, Rongyi Qian, Zhenning Ma, Xiaoqiong Lei, Jianyu Ling, Xu Liu, Guibin Zhang   +6 more
doaj   +1 more source

Modeling the Viscosity of Anhydrous and Hydrous Volcanic Melts

Geochemistry, Geophysics, Geosystems, 2021
The viscosity of volcanic melts is a dominant factor in controlling the fluid dynamics of magmas and thereby eruption style. It can vary by several orders of magnitude, depending on temperature, chemical composition, and water content. The experimentally
D. Langhammer, D. Di Genova, G. Steinle‐Neumann   +2 more
doaj   +1 more source

Enhanced Accuracy of Airborne Volcanic Ash Detection Using the GEOKOMPSAT-2A Satellite

Sensors, 2021
In this study, a technique facilitating the enhanced detection of airborne volcanic ash (VA) has been developed, which is based on the use of visible (VIS), near-infrared (NIR), and infrared (IR) bands by meteorological satellite systems.
Soi Ahn, Joon-Bum Jee, Kyu-Tae Lee, Hyun-Jong Oh   +3 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source