Results 41 to 50 of about 30,290 (300)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

RRS "Charles Darwin" Cruise 178, 14 Mar - 11 Apr 2006. 3D seismic acquisition over mud volcanoes in the Gulf of Cadiz and submarine landslides in the Eivissa Channel, western Mediterranean Sea [PDF]

open access: yes, 2006
The major aims of Charles Darwin Cruise 178 were to obtain (i) 3D seismic imagery, video transects and swath bathymetry maps of mud volcanoes in the southern Gulf of Cadiz, (ii) video transects across suspected cold water coral reefs in the Alboran Sea ...
Berndt, C., Masson, D.G.
core  

First-Arrival Tomography for Mountain Tunnel Hazard Assessment Using Unmanned Aerial Vehicle Seismic Source and Enhanced by Supervirtual Interferometry

open access: yesRemote Sensing
Preliminary tunnel surveys are essential for identifying geological hazards such as aquifers, faults, and karstic zones. While first-arrival tomography is effective for imaging shallow anomalies, traditional seismic sources face significant limitations ...
Jun Zhang   +6 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Volcanoes [PDF]

open access: yes, 2010
This slide presentation reviews the different types of volcanoes showing several views of current volcanic activity.
Willis, Kimberly
core   +3 more sources

Modeling the Viscosity of Anhydrous and Hydrous Volcanic Melts

open access: yesGeochemistry, Geophysics, Geosystems, 2021
The viscosity of volcanic melts is a dominant factor in controlling the fluid dynamics of magmas and thereby eruption style. It can vary by several orders of magnitude, depending on temperature, chemical composition, and water content. The experimentally
D. Langhammer   +2 more
doaj   +1 more source

Enhanced Accuracy of Airborne Volcanic Ash Detection Using the GEOKOMPSAT-2A Satellite

open access: yesSensors, 2021
In this study, a technique facilitating the enhanced detection of airborne volcanic ash (VA) has been developed, which is based on the use of visible (VIS), near-infrared (NIR), and infrared (IR) bands by meteorological satellite systems.
Soi Ahn   +3 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Mud Volcano Systems: Structure, Evolution and Processes [PDF]

open access: yes, 2011
Mud volcano systems erupt sediment and fluid onto the Earth’s surface producing edifices up to 25 km3 in volume however, little is known about how such volumes are transported through the Earth’s crust.
Roberts, Katie Sarah   +1 more
core  

The Mass Balance of the Kozelsky Glacier in Kamchatka for 1977–2022

open access: yesЛëд и снег, 2023
The change in the volume of the Kozelsky Glacier in Kamchatka for the period 1977–2022 (1977–2015 and 2015–2022) was estimated using historical data and modern DEM. During this period, the area of the glacier did not change much.
A. Ya. Muraviev   +4 more
doaj   +1 more source

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