Results 61 to 70 of about 181,923 (329)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

TSUNAMIGENIC SOURCES IN THE INDIAN OCEAN [PDF]

Science of Tsunami Hazards, 2008
Based on an assessment of the repeat periods of great earthquakes from past seismicity, convergence rates and paleoseismological results, possible future source zones of tsunami generating earthquakes in the Indian Ocean (possible seismic gap areas) are ...
B. K. Rastogi, R. K. Jaiswal, Tad S. Murty   +2 more
doaj  

AGU Centennial Grand Challenge: Volcanoes and Deep Carbon Global CO2 Emissions From Subaerial Volcanism—Recent Progress and Future Challenges

Geochemistry, Geophysics, Geosystems, 2020
Quantifying the global volcanic CO2 output from subaerial volcanism is key for a better understanding of rates and mechanisms of carbon cycling in and out of our planet and their consequences for the long‐term evolution of Earth's climate over geological
Tobias P. Fischer, Alessandro Aiuppa
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

In situ measurements of tropospheric volcanic plumes in Ecuador and Colombia during TC^4 [PDF]

, 2011
A NASA DC-8 research aircraft penetrated tropospheric gas and aerosol plumes sourced from active volcanoes in Ecuador and Colombia during the Tropical Composition, Cloud and Climate Coupling (TC^4) mission in July–August 2007. The likely source volcanoes
Anderson, B. E., Browell, E. V., Carn, S. A., Crounse, J., Dibb, J. E., Diskin, G., Froyd, K. D., Hair, J. W., Krotkov, N. A., Sachse, G., Spencer, K., Vay, S. A., Wennberg, P.   +12 more
core   +4 more sources

Volcanoes muon imaging using Cherenkov telescopes [PDF]

, 2015
A detailed understanding of a volcano inner structure is one of the key-points for the volcanic hazards evaluation. To this aim, in the last decade, geophysical radiography techniques using cosmic muon particles have been proposed.
Catalano, Osvaldo, Cusumano, Giancarlo, Del Santo, Melania, Maccarone, Maria Concetta, Mineo, Teresa, Pareschi, Giovanni   +5 more
core   +2 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Discovery of Ancient Volcanoes in the Okhotsk Sea (Russia): New Constraints on the Opening History of the Kurile Back Arc Basin

Geosciences, 2020
Here we present the first radiometric age and geochemical (major and trace element and isotope) data for samples from the Hydrographer Ridge, a back arc volcano of the Kurile Island Arc, and a newly discovered chain of volcanoes (“Sonne Volcanoes”) on ...
Reinhard Werner, Boris Baranov, Kaj Hoernle, Paul van den Bogaard, Folkmar Hauff, Igor Tararin   +5 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Modelling of earthquake swarms suggests magmatic fluids in the upper crust beneath the Eger Rift

Communications Earth & Environment
Earthquake swarms are enigmatic seismic phenomena that occur across diverse tectonic settings, from volcanic to intraplate regions, and are often associated with fluid migration, magmatic activity, or stress redistribution. The Northwest Bohemia/Vogtland
Pınar Büyükakpınar, Torsten Dahm, Sebastian Hainzl, Marius Isken, Matthias Ohrnberger, Jana Doubravová, Siegfried Wendt, Sigward Funke   +7 more
doaj   +1 more source