Results 61 to 70 of about 173,383 (330)

Volcanic Hot-Spot Detection Using SENTINEL-2: A Comparison with MODIS−MIROVA Thermal Data Series [PDF]

, 2020
In the satellite thermal remote sensing, the new generation of sensors with high-spatial resolution SWIR data open the door to an improved constraining of thermal phenomena related to volcanic processes, with strong implications for monitoring ...
Cigolini, Corrado, Coppola, Diego, Laiolo, Marco, Massimetti, Francesco, Ripepe, Maurizio, Valade, Sébastien   +5 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Discovery of Ancient Volcanoes in the Okhotsk Sea (Russia): New Constraints on the Opening History of the Kurile Back Arc Basin

Geosciences, 2020
Here we present the first radiometric age and geochemical (major and trace element and isotope) data for samples from the Hydrographer Ridge, a back arc volcano of the Kurile Island Arc, and a newly discovered chain of volcanoes (“Sonne Volcanoes”) on ...
Reinhard Werner, Boris Baranov, Kaj Hoernle, Paul van den Bogaard, Folkmar Hauff, Igor Tararin   +5 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Modelling of earthquake swarms suggests magmatic fluids in the upper crust beneath the Eger Rift

Communications Earth & Environment
Earthquake swarms are enigmatic seismic phenomena that occur across diverse tectonic settings, from volcanic to intraplate regions, and are often associated with fluid migration, magmatic activity, or stress redistribution. The Northwest Bohemia/Vogtland
Pınar Büyükakpınar, Torsten Dahm, Sebastian Hainzl, Marius Isken, Matthias Ohrnberger, Jana Doubravová, Siegfried Wendt, Sigward Funke   +7 more
doaj   +1 more source

TSUNAMIGENIC SOURCES IN THE INDIAN OCEAN [PDF]

Science of Tsunami Hazards, 2008
Based on an assessment of the repeat periods of great earthquakes from past seismicity, convergence rates and paleoseismological results, possible future source zones of tsunami generating earthquakes in the Indian Ocean (possible seismic gap areas) are ...
B. K. Rastogi, R. K. Jaiswal, Tad S. Murty   +2 more
doaj  

Magma Fracking Beneath Active Volcanoes Based on Seismic Data and Hydrothermal Activity Observations

Geosciences, 2020
Active volcanoes are associated with microearthquake (MEQ) hypocenters that form plane-oriented cluster distributions. These are faults delineating a magma injection system of dykes and sills.
Alexey Kiryukhin, Evgenia Chernykh, Andrey Polyakov, Alexey Solomatin   +3 more
doaj   +1 more source

Gas emission strength and evolution of the molar ratio of BrO/SO2 in the plume of Nyiragongo in comparison to Etna [PDF]

, 2015
Airborne and ground-based differential optical absorption spectroscopy observations have been carried out at the volcano Nyiragongo (Democratic Republic of Congo) to measure SO2 and bromine monoxide (BrO) in the plume in March 2004 and June 2007 ...
Aiuppa, Aiuppa, Aiuppa, Aiuppa, Aiuppa, Bobrowski, Bobrowski, Bobrowski, Bobrowski, Bobrowski, Boichu, Bureau, Carn, Chakrabarti, Delmelle, Dorf, Durieux, Ebinger, Fitzenberger, Galle, Galle, Gerlach, Gerlach, Gerlach, Giggenbach, Glasow, Glasow, Glasow, Glasow, Halmer, Honda, Horrocks, Hönninger, Kelly, Kern, Kitto, Komorowski, Kutterolf, Lary, Lazrus, Martin, Martin, Noguchi, Oppenheimer, Parrella, Pennisi, Pinto, Platt, Pundt, Pyle, Richter, Richter, Roberts, Robock, Rogers, Rogers, Saiz-Lopez, Salawitch, Sawyer, Schofield, Schofield, Sedlacek, Shinohara, Sturges, Surl, Symonds, Tazieff, Theys, Theys, Wennberg, Witt, Wittmer, Woods, Yang   +73 more
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

A porous flow model of flank eruptions on Mt. Etna: second-order perturbation theory

Annals of Geophysics, 1997
A porous flow model for magma migration from a deep source within a volcanic edifice is developed. The model is based on the assumption that an isotropic and homogeneous system of fractures allows magma migration from one localized feeding dyke up to the
N. Cenni, M. Bonafede
doaj   +1 more source