Results 301 to 310 of about 57,133 (342)

Voltage‐dependent anion channels: Key players in viral infection

Reviews in Medical Virology, 2023
AbstractViruses control the host cell by exploiting its molecular machinery to facilitate viral replication and propagation. Understanding different viral mechanisms and biochemical pathways is crucial for finding promising therapeutic solutions to viral infections. The mitochondrion is a vital organelle targeted by various types of viruses.
Ahmed H. Saadawy   +4 more
openaire   +2 more sources

Voltage-dependent anion channel in mammalian spermatozoa

Biochemical and Biophysical Research Communications, 2010
Voltage-dependent anion channel (VDAC) is a multi-functional channel protein in the mitochondrial outer membrane of all eukaryotes. It is involved in extensive physiological and pathophysiological processes. However there is only scant information about VDAC in mammalian reproduction, fertility and development in the past.
Bianjiang, Liu   +2 more
openaire   +2 more sources

Quinidine partially blocks mitochondrial voltage-dependent anion channel (VDAC)

European Biophysics Journal, 2020
Quinidine is an antiarrhythmic drug commonly used for the treatment of cardiac ailments. It affects oxidative phosphorylation, calcium uptake, and ion channels of mitochondria. We have investigated the interaction of Quinidine and mitochondrial voltage-dependent anion channel (VDAC).
Chetan Malik, Subhendu Ghosh
openaire   +2 more sources

The functions of voltage-dependent anion channels in plants

Apoptosis, 2013
Voltage-dependent anion channels (VDACs), known as outer mitochondrial membrane proteins, are present in all eukaryotic cells. In mammals, they are now recognized to play crucial roles in the regulation of metabolic and energetic functions of mitochondria as well as in mitochondria-mediated apoptosis, in association with various proteins and non ...
Yoshihiro, Takahashi, Chika, Tateda
openaire   +2 more sources

Voltage-Dependent Anion Channel Transports Calcium Ions through Biomimetic Membranes

Langmuir, 2007
The mitochondrial outer membrane channel (VDAC), a central player in mitochondria and cell death, was reconstituted in polymer-supported phospholipid bilayers. Highly purified VDAC was first reconstituted in vesicles; channel properties and NADH-ferricyanide reductase activity were ascertained before deposition onto solid substrates.
Deniaud, Aurélien   +7 more
openaire   +4 more sources

Cellular Interactome of Mitochondrial Voltage-Dependent Anion Channels: Oligomerization and Channel (Mis)Regulation

ACS Chemical Neuroscience, 2021
Voltage-dependent anion channels (VDACs) of the outer mitochondrial membrane are known conventionally as metabolite flux proteins. However, research findings in the past decade have revealed the multifaceted regulatory roles of VDACs, from governing cellular physiology and mitochondria-mediated apoptosis to directly regulating debilitating cancers and ...
Altmash Khan   +2 more
openaire   +2 more sources

The voltage-dependent anion channel: an essential player in apoptosis

Biochimie, 2002
The increase of outer mitochondrial membrane permeability is a central event in apoptotic cell death, since it releases several apoptogenic factors such as cytochrome c into the cytoplasm that activate the downstream destructive processes. The voltage-dependent anion channel (VDAC or mitochondrial porin) plays an essential role in the increase of ...
Yoshihide, Tsujimoto, Shigeomi, Shimizu
openaire   +2 more sources

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