Results 31 to 40 of about 21,928 (305)
Cell-free electrophysiology of human VDACs incorporated into nanodiscs: An improved method
Biophysical Reports, 2021 Voltage-dependent anion-selective channel (VDAC) is one of the main proteins of the outer mitochondrial membrane of all eukaryotes, where it forms aqueous, voltage-sensitive, and ion-selective channels.
Stefano Conti Nibali +5 more
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MicroED structure of lipid-embedded mammalian mitochondrial voltage-dependent anion channel [PDF]
Proceedings of the National Academy of Sciences, 2020 Significance Microcrystal electron diffraction (MicroED) is an electron cryo-microscopy (cryoEM) method for determining structures using submicron crystals. Until now, determining structures of membrane proteins by MicroED required that the protein crystals be in a solution amenable to standard cryoEM blotting and vitrification ...
Michael W. Martynowycz +4 more
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SWELL1 is a glucose sensor regulating β-cell excitability and systemic glycaemia
Nature Communications, 2018 Insulin secretion by β-cells is stimulated by glucose and is dependent on the induction of β-cell membrane depolarization, mainly driven by the closure of KATP channels, which in turn promotes voltage-gated Ca2+ channel opening. Here Kang et al.
Chen Kang +10 more
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Frontiers in Physiology, 2021 The voltage-dependent anion-selective channel (VDAC) is a porin in the mitochondrial outer membrane (MOM). Unlike bacterial porins, several mitochondrial β-barrels comprise an odd number of β-strands, as is the case for the 19-β-stranded VDAC. Previously,
Fraser G. Ferens +5 more
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Frontiers in Plant Science, 2021 In plants, programmed cell death (PCD) is involved in both the development and the response to biotic and abiotic aggressions. In early stages of PCD, mitochondrial membranes are made permeable by the formation of permeability transition pores, whose ...
Karla J. Rojas-Méndez +4 more
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Isolation of a novel human voltage-dependent anion channel gene [PDF]
European Journal of Human Genetics, 1998 The voltage-dependent anion channel of the mitochondrial outer membrane (VDAC) is a small, abundant pore-forming protein found in the outer membranes of all eukaryotic mitochondria. The VDAC protein is believed to control the movement of adenine nucleotides through the outer membrane and to be the mitochondrial binding site for hexokinase and glycerol ...
Z, Rahmani, C, Maunoury, A, Siddiqui
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Recombinant yeast VDAC2: a comparison of electrophysiological features with the native form
FEBS Open Bio, 2019 Voltage‐dependent anion channel isoform 2 of the yeast Saccharomyces cerevisiae (yVDAC2) was believed for many years to be devoid of channel activity. Recently, we isolated yVDAC2 and showed that it exhibits channel‐forming activity in the planar lipid ...
Andrea Magrì +7 more
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Bio-Protocol, 2017 Two-Electrode Voltage-Clamp (TEVC) recording in Xenopus laevis oocytes provides a powerful method to investigate the functions and regulation of ion channel proteins.
cun wang, Jingbo Zhang, Julian Schroeder
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Novel hybrid action of GABA mediates inhibitory feedback in the mammalian retina.
PLoS Biology, 2019 The stream of visual information sent from photoreceptors to second-order bipolar cells is intercepted by laterally interacting horizontal cells that generate feedback to optimize and improve the efficiency of signal transmission.
James C R Grove +7 more
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Intracellular ion channels and cancer
Frontiers in Physiology, 2013 Several types of channels play a role in the maintenance of ion homeostasis in subcellular organelles including endoplasmatic reticulum, nucleus, lysosome, endosome and mitochondria.
Luigi eLeanza +5 more
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