Results 81 to 90 of about 4,139,382 (260)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Loss comparison of 2 and 3-level inverter topologies

open access: yes, 2010
This paper investigates semiconductor and DC-link capacitor losses in two two-level and two three-level voltage source inverters. The components of the four inverters are selected to have appropriate voltage and current ratings.
Orfanoudakis, G.   +3 more
core   +1 more source

Corrected complex torque coefficient method for synchronization stability analysis of grid‐connected VSC

open access: yesIET Renewable Power Generation
Sub‐synchronous oscillation of grid‐connected voltage source converter (VSC) dominated by phase locked loop (PLL) is an important stability issue in nowadays power systems.
Boyuan Zhao   +4 more
doaj   +1 more source

Multi-objective optimal scheduling strategy for wind power, PV and pumped storage plant in VSC-HVDC grid

open access: yesThe Journal of Engineering, 2019
Zhangbei demonstration project will be the world's highest voltage level and largest capacity VSC-HVDC power grid, by which millions of kilowatts of renewable energy and pumped storage power will be supplied to Beijing.
Man Xu, Linlin Wu, Hui Liu, Xiao Wang
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Reliability modelling and analysis on MMC for VSC-HVDC by considering the press-pack IGBT and capacitors failure

open access: yesThe Journal of Engineering, 2019
Modular multi-level converter (MMC) with press-packing IGBT devices is the popular and key equipment of VSC-HVDC system, its reliability is directly related to the equipment safe operation.
Li Hui   +6 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Modelling and analysis on short-circuit failure for press-pack IGBT devices used in VSC-HVDC converter

open access: yesThe Journal of Engineering, 2019
Press-pack insulated gate bipolar transistor (IGBT) device is the key component in the voltage source converter high voltage direct current (VSC-HVDC) due the advantage of the short-circuit failure.
Ran Yao   +9 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Study on the resonance stability problem of the wind power base with the MMC–HVDC system

open access: yesThe Journal of Engineering, 2019
Considering the negative resistance effect of power electronic equipment, unstable resonance problems may occur between wind farms and converter stations.
Facai Xing   +5 more
doaj   +1 more source

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