Results 81 to 90 of about 581 (271)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Avaliação do comportamento de aerogeradores de velocidde fixa e variável integrados em redes elétricas fracas [PDF]

, 2003
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Elétrica.Esta tese apresenta propostas para o aumento da margem de estabilidade transitória pós-falta de sistemas elétricos com grande ...
Nunes, Marcus Vinicius Alves
core  

Power cable stresses caused by transmission line faults in next generation VSC-MMC systems

The Journal of Engineering, 2019
Until today, HVDC systems based on Modular Multilevel Voltage Source Converters (VSC-MMC) have exclusively been realised with cross-linked polyethylene (XLPE) cable transmission in monopolar configuration.
Philipp Tünnerhoff, Philipp Ruffing, Philipp Ruffing, Ralf Puffer   +3 more
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Metrology for high voltage direct current state-of-art and current development [PDF]

, 2011
Energy transmission by high voltage direct current - HVDC - is steadily increasing in the world, both at the highest power levels, but also at medium power, for example in connections of remote wind-parks to the main a.c. grid.
Bergman, Anders,
core  

A second‐order sliding mode control with active disturbance rejection for dynamic voltage restorers

IET Power Electronics
This paper proposes an extended state observer (ESO)‐based second‐order sliding mode control (SMC) for dynamic voltage restorers (DVRs). Unlike the conventional first‐order SMC and some second‐order SMC (SOSMC) methods that suffer from chattering, the ...
Farzaneh Bagheri, Samet Biricik, Hafiz Ahmed, Hasan Komurcugil   +3 more
doaj   +1 more source

Modelling and control of a back-to-back MMC–HVDC system using ADPSS

The Journal of Engineering, 2019
Back-to-back modular multilevel converter–high-voltage direct current (MMC–HVDC) can realise the asynchronous interconnection of two regional power grids. It can effectively solve the power grid stability problems caused by AC–DC power transfer and avoid
Pucheng Cai, Wang Xiang, Jinyu Wen
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Report of multijunction thermal convertor interlaboratory comparison study for measurements at Sandia National Laboratory. [PDF]

, 2009
Two Multijunction Thermal Voltage Converters (MJTCs) were provided to the Sandia National Laboratory Primary Standards Laboratory (Sandia PSL) as part of an interlaboratory comparison (ILC).
Klemme, Beverly J., Beverly Klemme
core   +1 more source

Variable DC voltage based reactive power enhancement scheme for MMC‐STATCOM

IET Smart Grid
Constrained by the AC voltage amplitude modulated by a modular multilevel converter‐based static synchronous compensator (MMC‐STATCOM), its reactive power output may be subject to oscillations under grid contingencies, posing a threat to the grid stable ...
Lujie Yu, Guoyan Wang, Tong Wu, Jiebei Zhu, Campbell D. Booth   +4 more
doaj   +1 more source