Results 101 to 110 of about 125,675 (299)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Dynamic weighting factor assignment method for the predictive control of electrical drives

IET Power Electronics
This article presents an innovative approach for real‐time allocation of weighting factor values in model predictive control of electrical drive systems.
Kristóf Bándy, Péter Stumpf
doaj   +1 more source

CalFUSE v3: A Data-Reduction Pipeline for the Far Ultraviolet Spectroscopic Explorer

, 2007
Since its launch in 1999, the Far Ultraviolet Spectroscopic Explorer (FUSE) has made over 4600 observations of some 2500 individual targets. The data are reduced by the Principal Investigator team at the Johns Hopkins University and archived at the ...
A. W. Fullerton, B. Godard, D. Massa, D. J. Lindler, D. J. Sahnow, J. Dupuis, J. W. Kruk, J.‐C. Hsu, M. E. Kaiser, M. L. Romelfanger, P. Sonnentrucker, P. E. Barrett, R. D. Robinson, S. Lacour, T. Civeit, Tremsin A. S., W. V. Dixon   +16 more
core   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Decentralized Control of DC Microgrids Using Interconnection and Damping Assignment Passivity-Based Control Technique: Experimental Verification

IEEE Access
A decentralized control approach is introduced in this paper that utilizes passivity-based control for two DC-distributed energy sources supplying the power of a load. Considering the concept of passivity, if each distributed generator exhibits passivity,
Mohammad Afkar, Cong Yuan, Roghayeh Gavagsaz-Ghoachani, Wiset Saksiri, Matheepot Phattanasak, Jean-Philippe Martin, Serge Pierfederici   +6 more
doaj   +1 more source

Do Customers Choose Proper Tariff? Empirical Analysis Based on Polish Data Using Unsupervised Techniques

Energies, 2018
Individual electricity customers that are connected to low voltage network in Poland are usually assigned to the most common G11 tariff group with flat prices for the whole year, no matter the usage volume.
Rafik Nafkha, Krzysztof Gajowniczek, Tomasz Ząbkowski   +2 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Shunt active power filter using model predictive control with stability guarantee

e-Prime: Advances in Electrical Engineering, Electronics and Energy
This paper presents a model predictive control (MPC) strategy to solve an optimization problem based on system state and control variables, subject to constraints imposed by the control objective.
Jhon Pérez-Ramírez, Diego Montoya-Acevedo, Walter Gil-González, Oscar Danilo Montoya, Carlos Restrepo   +4 more
doaj   +1 more source

Observations on the construction of covers using permutation voltage assignments

Discrete Mathematics, 1979
AbstractIn the usual treatment of covering spaces, the algebraic object associated with a cover is a conjugacy class of subgroups of the fundamental group of the target space. For finite degree covers, one could as easily choose the algebraic object to be a class of homomorphisms from the fundamental group of the target space to the symmetric group on ...
openaire   +1 more source