Results 91 to 100 of about 20,714 (266)

Comparative analysis of principal modulation techniques for modular multilevel converter and a modified reduced switching frequency algorithm for nearest level pulse width modulation

Electrical engineering & Electromechanics
Introduction. The Modular Multilevel Converter (MMC) is an advanced topology widely used in medium and high-power applications, offering significant advantages over other multilevel converters, including high efficiency and superior output waveform ...
M. Benboukous, H. Bahri, M. Talea, M. Bour, K. Abdouni   +4 more
doaj   +1 more source

Voltage Balancing on Three-phase Low Voltage Feeder

, 2015
Voltage imbalance in low voltage (LV) networks is expected to deteriorate as low carbon technologies, e.g. electric vehicles (EVs) and heat pumps (HPs) are increasingly deployed. The new electrical demand attributable to EVs and HPs would increase the voltage magnitude variation, increasing the possibility of voltages moving outside the statutory LV ...
openaire   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Four-Level Single-Stage Single-Source Boost-Inverter

IEEE Access
This paper presents a novel concept of a DC-AC converter that ensures AC voltage modulation on four levels using a single branch and achieves voltage boosting.
Robert Stala, Szymon Folmer, Zbigniew Waradzyn, Adam Penczek, Stanislaw Pirog, Aleksander Skala, Andrzej Mondzik, Krishna Kumar Gupta, Pallavee Bhatnagar, Sanjay K. Jain   +9 more
doaj   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

A Mutual Inductance–Capacitance IPOS-Type Self-Balancing LLC Resonant Converter

Energies
In low-voltage-input, high-voltage-output applications, the input-parallel output-series (IPOS) LLC resonant converter experiences voltage and current imbalances due to parameter mismatches in resonant tank components.
Jin Li, Ao Liu, Weiyi Tang
doaj   +1 more source