Results 71 to 80 of about 3,069,371 (299)
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Voltage-dependent anion channels: different isoforms for different functions [PDF]
The Voltage-dependent anion channel (VDAC) is the most abundant protein of the outer mitochondrial membrane (OMM) and mediates the flow of ions and metabolites between the cytoplasm and the mitochondrial network.
DE STEFANI, Diego, De Stefani, D.
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
An Improved Control Strategy for Three-Phase Power Inverters in Islanded AC Microgrids
Microgrids (MGs) are composed of multiple distributed generators (DGs) interfaced to micronetwork through paralleled connected power inverters (PIs). Load sharing among multiple DG units is an important task for autonomous operation of microgrids.
Muhammad Zahid Khan +4 more
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Voltage and reactive power coordinated control strategy for flexible on-load tap changer
As the increasing proportion of renewable energy and power electronic devices in the power grid, voltage fluctuations are becoming frequent. In response to the current voltage regulation and reactive power compensation requirements of the distribution ...
LIU Shui +4 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Regulation of neuronal excitability through pumilio-dependent control of a sodium channel gene [PDF]
Dynamic changes in synaptic connectivity and strength, which occur during both embryonic development and learning, have the tendency to destabilize neural circuits.
Baines, Richard A.; id_orcid +5 more
core +1 more source
A state-based potential game approach for distributed voltage regulation in distribution networks
With the increasing penetration rate of renewable energy sources over recent years, voltage fluctuations and violations due to the inherent intermittency of renewable energy sources pose a great challenge to the safe and steady operation of distribution ...
PAN Jiangchao +4 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source

