Results 71 to 80 of about 47,285 (266)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Voltage Control Approach With Dynamic Voltage Reference for PV Distributed Generation Operating Under Cloud-Induced Shading Conditions

open access: yesIEEE Access
The integration of photovoltaic generation into distribution systems can deteriorate the system voltage and the conventional voltage regulation process based on step voltage regulators. The system operation under cloud conditions is much more challenging
Glorio Arnaldo Landbrug   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A 21-Gb/s Dual-Channel Voltage-Mode Transmitter With Stacked NRZ and PAM4 Drivers

open access: yesIEEE Access, 2018
This paper describes a voltage-mode transmitter that stacks independent non-return-tozero (NRZ) and four-level pulse amplitude modulation (PAM4) drivers for dual channels.
Sung-Ha Kim   +4 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Enhancing power distribution performance through simultaneous optimization of voltage regulators placement and conductor selection: A multi-period MILP approach

open access: yesResults in Engineering
Maintaining optimal voltage profiles and minimizing technical losses are critical challenges in power distribution systems, particularly under significant load fluctuations.
Luis A. Gallego Pareja   +2 more
doaj   +1 more source

Introducing The Radiation-Hardened Voltage Regulators Rhfl4913 and the Rhfl6000

open access: yesE3S Web of Conferences, 2017
With the progressive scaling of the modern CMOS processes arising during the recent years, for the devices operating in space the susceptivity to the over-voltage events has increased. They have become more stringent the requirements in terms of accuracy
Bonna G., Ribellino C., Pappalardo S.
doaj   +1 more source

Home - About - Disclaimer - Privacy