Results 101 to 110 of about 125,876 (264)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Direct regulation of the voltage sensor of HCN channels by membrane lipid compartmentalization. [PDF]
Nat Commun, 2023 Handlin LJ, Dai G.
europepmc +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Design of a wireless monitoring system based on the ZigBee protocol for photovoltaic systems
, 2011 This thesis was submitted for the degree of Master of Philosophy and awarded by Brunel University.This work deals with the possibility of using the promising technology of wireless sensor networks (WSN) in the field of photovoltaic (PV) plant supervising
Katsioulis, Vasileios
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Teaching old sensors New tricks: archetypes of intelligence
, 2007 In this paper a generic intelligent sensor software architecture is described which builds upon the basic requirements of related industry standards (IEEE 1451 and SEVA BS- 7986). It incorporates specific functionalities such as real-time fault detection,
White, Neil M. +3 more
core
Ion currents through the voltage sensor domain of distinct families of proteins. [PDF]
J Biol Phys, 2023 Arcos-Hernández C, Nishigaki T.
europepmc +1 more source