Results 81 to 90 of about 125,876 (264)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Bi12TiO20 FIBER OPTIC VOLTAGE SENSOR FOR INDUSTRIAL APPLICATIONS [PDF]

open access: yes, 2004
"The content of the present dissertation is a contribution to these multiple applications that has the fiber optics in the land of the science. In particular, the study concentrates on the use of the optic fiber as a guide of luminous wave besides an ...
FRANCISCO GERARDO PEÑA LECONA
core  

Distributed photonic instrumentation for smart grids

open access: yes, 2013
Photonic sensor networks possess the unique potential to provide the instrumentation infrastructure required in future smart grids by simultaneously addressing the issues of metrology and communications.
Pawel Niewczas   +13 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Improvement of Pulse Voltage Generated by Wiegand Sensor Through Magnetic-Flux Guidance

open access: yes, 2020
Magnetization reversal in a Wiegand wire induces a pulse voltage in the pickup coil around the wire, called the Wiegand pulse. The Wiegand sensor features the Wiegand wire and the pickup coil.
Takafumi Sakai   +4 more
core   +1 more source

Supercapacitor leakage in energy-harvesting sensor nodes: fact or fiction? [PDF]

open access: yes, 2012
As interest in energy-harvesting sensor nodes continues to grow, the use of supercapacitors as energy stores or buffers is gaining popularity. The reasons for their use are numerous, and include their high power density, simple interfacing requirements ...
Geoff V. Merrett   +3 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Design of a single-chip pH sensor using a conventional 0.6-μm CMOS process [PDF]

open access: yes, 2004
A pH sensor fabricated on a single chip by an unmodified, commercial 0.6-/spl μm CMOS process is presented. The sensor comprises a circuit for making differential measurements between an ion-sensitive field-effect transistor (ISFET) and a reference ...
Ali, D.   +8 more
core   +1 more source

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