Results 31 to 40 of about 4,346 (212)
Voltage sensors: challenging, but with potential [PDF]
Nature Methods, 2015 Genetically encoded voltage sensors are coming of age, but their use still poses challenges that must be addressed from multiple angles.
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Study and Experiment on Non-Contact Voltage Sensor Suitable for Three-Phase Transmission Line
Sensors, 2015 A voltage transformer, as voltage signal detection equipment, plays an important role in a power system. Presently, more and more electric power systems are adopting potential transformer and capacitance voltage transformers. Transformers are often large
Qiang Zhou +4 more
doaj +1 more source
Two separate interfaces between the voltage sensor and pore are required for the function of voltage-dependent K(+) channels. [PDF]
PLoS Biology, 2009 Voltage-dependent K(+) (Kv) channels gate open in response to the membrane voltage. To further our understanding of how cell membrane voltage regulates the opening of a Kv channel, we have studied the protein interfaces that attach the voltage-sensor ...
Seok-Yong Lee +3 more
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eLife, 2018 Voltage-sensing phosphatases (VSP) contain a voltage sensor domain (VSD) similar to that of voltage-gated ion channels but lack a pore-gate domain. A VSD in a VSP regulates the cytoplasmic catalytic region (CCR).
Akira Kawanabe +9 more
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The secret lives of voltage sensors [PDF]
The Journal of Physiology, 2007 Voltage-gated ion channels serve a wide array of biological purposes. In one well-known example, they orchestrate the action potential in the excitable cells of nervous tissue thus generating excitability throughout the nervous system. This diverse family of transmembrane proteins is exquisitely sensitive to membrane potential and many of its members ...
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Proton currents constrain structural models of voltage sensor activation
eLife, 2016 The Hv1 proton channel is evidently unique among voltage sensor domain proteins in mediating an intrinsic ‘aqueous’ H+ conductance (GAQ). Mutation of a highly conserved ‘gating charge’ residue in the S4 helix (R1H) confers a resting-state H+ ‘shuttle ...
Aaron L Randolph +4 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille +9 more
wiley +1 more source
Grid voltage sensor fault‐tolerant control for single‐phase two‐level PWM rectifier
IET Electric Power Applications, 2022 The main purpose of this work is to address the problem of robust grid voltage sensor fault‐tolerant control for a single‐phase two‐level rectifier. First, considering a rectifier with disturbances and grid voltage sensor fault, the standard switched ...
Zifeng Gong +4 more
doaj +1 more source
Toxins, 2021 The voltage-gated sodium channel NaV1.7 is an important target for drug development due to its role in pain perception. Recombinant expression of full-length channels and their use for biophysical characterization of interactions with potential drug ...
Ryan V. Schroder +4 more
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