Results 11 to 20 of about 125,876 (264)
Electric fingerprint of voltage sensor domains [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2014 Significance A central paradigm in the subject of cellular excitability is whether or not a dynamic membrane voltage field contributes to the operation of voltage sensor proteins. This issue has challenged an entire generation of scientists because static and dynamic contributions of the field cannot be discriminated from electrophysiology ...
Caio S Souza +2 more
exaly +3 more sources
Similar voltage-sensor movement in spHCN channels can cause closing, opening, or inactivation. [PDF]
J Gen Physiol, 2023 Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels contribute to the rhythmic firing of pacemaker neurons and cardiomyocytes. Mutations in HCN channels are associated with cardiac arrhythmia and epilepsy.
Wu X +4 more
europepmc +2 more sources
Voltage Sensor Movements during Hyperpolarization in the HCN Channel [PDF]
Cell, 2019 Chia-Hsueh Lee, Roderick Mackinnon
exaly +2 more sources
A Voltage-Sensor Water Pore [PDF]
Biophysical Journal, 2006 Voltage-sensor (VS) domains cause the pore of voltage-gated ion channels to open and close in response to changes in transmembrane potential. Recent experimental studies suggest that VS domains are independent structural units. This independence is revealed dramatically by a voltage-dependent proton-selective channel (Hv), which has a sequence ...
Freites, J Alfredo +2 more
openaire +3 more sources
Voltage Sensor Movements [PDF]
The Journal of General Physiology, 2002 The voltage dependence of K+, Na+, and Ca2+ channels is brought about by a voltage sensor that moves ∼12–13 e across the entire electric field ([Schoppa et al., 1992][1]; [Hirschberg et al., 1996][2]; [Noceti et al., 1996][3]).
openaire +2 more sources
Molecular mechanisms of the coupling of gating to voltage sensing in transmembrane proteins [PDF]
, 2014 Voltage gated potassium ion (Kv) channels regulate action potentials of the nervous system by responding to changes in transmembrane voltage, enabling K+ transport across the membrane to restore cells to their resting potential.
Starek, Greg
core +1 more source
Uncooperative Voltage Sensors [PDF]
Journal of General Physiology, 2009 A typical voltage-gated potassium (Kv) or sodium channel is exquisitely sensitive to small changes of membrane potential, so much so that a depolarization of
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Voltage Sensor Inactivation in Potassium Channels [PDF]
Frontiers in Pharmacology, 2012 In voltage-gated potassium (Kv) channels membrane depolarization causes movement of a voltage sensor domain. This conformational change of the protein is transmitted to the pore domain and eventually leads to pore opening. However, the voltage sensor domain may interact with two distinct gates in the pore domain: the activation gate (A-gate), involving
Bähring, Robert +3 more
openaire +3 more sources
Epidermal Passive RFID Strain Sensor for Assisted Technologies [PDF]
, 2014 An epidermal passive wireless strain sensor using RFID tags is presented. The tag is intended to detect eyebrow or neck skin stretch where paraplegic patients have the capability to tweak facial muscles.
Rumens, C.V. +3 more
core +1 more source
Optimization of soot deposition by high-temperature prepolarization of a resistive particulate matter sensor [PDF]
, 2020 For the purposes of the onboard diagnosis (OBD) of diesel particulate filters (DPFs) in diesel exhaust treatment systems, a particulate matter (PM) sensor is applied downstream from the DPFs to detect small amounts of diesel soot that passed through the ...
Fritze, Holger +2 more
core +1 more source