Results 21 to 30 of about 125,876 (264)

The Voltage Sensor in Voltage-Dependent Ion Channels [PDF]

Physiological Reviews, 2000
In voltage-dependent Na, K, or Ca channels, the probability of opening is modified by the membrane potential. This is achieved through a voltage sensor that detects the voltage and transfers its energy to the pore to control its gate. We present here the theoretical basis of the energy coupling between the electric field and the voltage, which allows ...
openaire   +2 more sources

High Voltage Optical Fibre Sensor for Use in Wire Relay Electrical Protection Systems [PDF]

, 2016
The last few decades have a wide spread use of optical fibre sensors in many applications. Optical fibre sensors have significant benefits over existing conventional sensors such as; high immunity to electromagnetic interference, the ability to transmit ...
Bashour, Rami
core   +1 more source

Voltage sensors: challenging, but with potential [PDF]

Nature Methods, 2015
Genetically encoded voltage sensors are coming of age, but their use still poses challenges that must be addressed from multiple angles.
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The secret lives of voltage sensors [PDF]

The Journal of Physiology, 2007
Voltage-gated ion channels serve a wide array of biological purposes. In one well-known example, they orchestrate the action potential in the excitable cells of nervous tissue thus generating excitability throughout the nervous system. This diverse family of transmembrane proteins is exquisitely sensitive to membrane potential and many of its members ...
openaire   +2 more sources

Voltage sensor of ion channels and enzymes [PDF]

Biophysical Reviews, 2011
Placed in the cell membrane (a two-dimensional environment), ion channels and enzymes are able to sense voltage. How these proteins are able to detect the difference in the voltage across membranes has attracted much attention, and at times, heated debate during the last few years.
Carlos, Gonzalez, Gustavo F, Contreras, Alexander, Peyser, Peter, Larsson, Alan, Neely, Ramón, Latorre   +5 more
openaire   +2 more sources

End effects in linear tubular motors and compensated position sensorless control based on pulsating voltage injection [PDF]

, 2011
The sensorless position control of permanent-magnet (PM) synchronous motors can be successfully implemented by superimposing a high-frequency voltage signal on the control voltage.
CUPERTINO, Francesco, Pellegrino G, Cupertino, F., SALVATORE L., Pellegrino, Gian-Mario Luigi, CUPERTINO F, Giangrande, P., Salvatore, L., GIANGRANDE P, PELLEGRINO, GIAN - MARIO LUIGI   +9 more
core   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Intermediate state trapping of a voltage sensor [PDF]

Journal of General Physiology, 2012
Voltage sensor domains (VSDs) regulate ion channels and enzymes by undergoing conformational changes depending on membrane electrical signals. The molecular mechanisms underlying the VSD transitions are not fully understood. Here, we show that some mutations of I241 in the S1 segment of the Shaker Kv channel positively shift the voltage dependence of ...
Lacroix, Jérôme J, Pless, Stephan Alexander, Maragliano, Luca, Campos, Fabiana V, Galpin, Jason D, Ahern, Christopher A, Roux, Benoît, Bezanilla, Francisco   +7 more
openaire   +3 more sources

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa, Shou Xu, Mark Zobeck, Sarah E. Sartain, Nino Rainusso, Lisa Wang, Nicole Montgomery, Paige Wheaton, Sarah Whittle   +8 more
wiley   +1 more source