Results 41 to 50 of about 417,703 (296)

The Voltage Sensor in Voltage-Dependent Ion Channels [PDF]

open access: yesPhysiological Reviews, 2000
In voltage-dependent Na, K, or Ca channels, the probability of opening is modified by the membrane potential. This is achieved through a voltage sensor that detects the voltage and transfers its energy to the pore to control its gate. We present here the theoretical basis of the energy coupling between the electric field and the voltage, which allows ...
openaire   +2 more sources

Electric fingerprint of voltage sensor domains [PDF]

open access: yesProceedings of the National Academy of Sciences, 2014
Significance A central paradigm in the subject of cellular excitability is whether or not a dynamic membrane voltage field contributes to the operation of voltage sensor proteins. This issue has challenged an entire generation of scientists because static and dynamic contributions of the field cannot be discriminated from electrophysiology ...
Caio S, Souza   +2 more
openaire   +2 more sources

Potential Early Risk Biomarkers for Reduced Forced Expiratory Volume in Children Post‐Hematopoietic Cell Transplantation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT We sought to identify potential early risk biomarkers for lung disease in children post‐allogeneic HCT. Patients with pulmonary function tests 3 months post‐transplant and plasma samples between days 7 and 14 post‐HCT were included. Six of 27 subjects enrolled had reduced forced expiratory volume 1 (FEV1) z scores.
Isabella S. Small   +3 more
wiley   +1 more source

Binding of Hanatoxin to the Voltage Sensor of Kv2.1

open access: yesToxins, 2012
Hanatoxin 1 (HaTx1) is a polypeptide toxin isolated from spider venoms. HaTx1 inhibits the voltage-gated potassium channel kv2.1 potently with nanomolar affinities. Its receptor site has been shown to contain the S3b-S4a paddle of the voltage sensor (VS).
Shin-Ho Chung, Anna Robinson, Rong Chen
doaj   +1 more source

Temperature compensation of digital inertial sensors [PDF]

open access: yes, 1974
Heaters for thermal stabilization are unnecessary when analog dc voltage provided by gyroscope temperature sensor is used to change outputs to compensate for temperature variations.
Hand, P. J.
core   +1 more source

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus   +6 more
wiley   +1 more source

The hydrophobic nature of a novel membrane interface regulates the enzyme activity of a voltage-sensing phosphatase

open access: yeseLife, 2018
Voltage-sensing phosphatases (VSP) contain a voltage sensor domain (VSD) similar to that of voltage-gated ion channels but lack a pore-gate domain. A VSD in a VSP regulates the cytoplasmic catalytic region (CCR).
Akira Kawanabe   +9 more
doaj   +1 more source

Grid voltage sensor fault‐tolerant control for single‐phase two‐level PWM rectifier

open access: yesIET Electric Power Applications, 2022
The main purpose of this work is to address the problem of robust grid voltage sensor fault‐tolerant control for a single‐phase two‐level rectifier. First, considering a rectifier with disturbances and grid voltage sensor fault, the standard switched ...
Zifeng Gong   +4 more
doaj   +1 more source

Tracking the movement of discrete gating charges in a voltage-gated potassium channel

open access: yeseLife, 2021
Positively charged amino acids respond to membrane potential changes to drive voltage sensor movement in voltage-gated ion channels, but determining the displacements of voltage sensor gating charges has proven difficult.
Michael F Priest   +2 more
doaj   +1 more source

Nutritional and Behavioral Intervention for Long‐Term Childhood Acute Leukemia Survivors With Metabolic Syndrome

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Metabolic syndrome (MetS) is a common complication in survivors of childhood acute lymphoblastic and myeloid leukemia (AL), and a major risk factor for premature cardiovascular disease, type‐2‐diabetes, and metabolic dysfunction‐associated steatotic liver disease (MASLD).
Visentin Sandrine   +10 more
wiley   +1 more source

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