Results 121 to 130 of about 565,077 (289)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
ELECTROSTATIC STRESS ANALYSIS OF HIGH VOLTAGE CABLES
International Journal of Research in Engineering and Technology, 2014 Power cable as one of the main components of power networks, play an important role in electric power transmission between different zones. In cable, stress will maximum nearer to the surface of the conductor and it will get decreases as we move away from core to outer sheath. So, dielectric will be unnecessarily strong and expensive.
openaire +1 more source
Partial Discharge in Electronic Equipments [PDF]
, 2009 Tato disertační práce se věnuje studiu částečných výbojů (PD) způsobených poklesem spolehlivosti a životnosti elektronických zařízení a systémů. Diagnostika PD je dnes známá metoda pro vysoké napětí u vysoko-výkonných zařízení.
Mammadov, Anar
core
On giant piezoresistance effects in silicon nanowires and microwires
, 2010 The giant piezoresistance (PZR) previously reported in silicon nanowires is experimentally investigated in a large number of surface depleted silicon nano- and micro-structures.
Arscott, S. +3 more
core +5 more sources
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Area-Delay-Energy Tradeoffs of Strain-Mediated Multiferroic Devices
, 2015 Multiferroic devices hold profound promise for ultra-low energy computing in beyond Moore's law era. The magnetization of a magnetostrictive shape-anisotropic single-domain nanomagnet strain-coupled with a piezoelectric layer in a multiferroic composite ...
Roy, Kuntal
core +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Input-output characterization of fiber composites by SH waves [PDF]
Input-output characterization of fiber composites is studied theoretically by tracing SH waves in the media. A fiberglass epoxy composite is modeled as a homogeneous transversely isotropic continuum plate.
Renneisen, John D. +1 more
core +1 more source