Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Computing Meaning, volume 1 Harry Bunt and Reinhard Muskens (editors) (Tilburg University) Dordrecht: Kluwer Academic Publishers (Studies in linguistics and philosophy, edited by Gennaro Chierchia, Pauline Jacobson, and Francis J. Pelletier, volume 73), 1999, vi+360 pp; hardbound, ISBN 0-7923-6108-3, $149.00, £93.00, Dfl 280.00 [PDF]
, 2001 Yoad Winter
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THE IMPACT OF THE 21ST CENTURY FOOD MARKETING ON CHILDREN'S BEHAVIOUR [PDF]
This paper aims to raise a question mark regarding children's food habits in the last decades in Romania, and how globalization, marketing and advertising influenced and changed our old romanian food prefferences.
Olar Ana - Elena, Tarcza Teodora Mihaela
core
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
The moss Physcomitrella patens. Annual Plant Reviews, Volume 36 [PDF]
, 2009 Jennifer K. Rowntree
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ANALYSIS OF ECONOMIC GAPS BETWEEN URBAN AND RURAL ROMANIAN AREAS [PDF]
In this paper the authors will perform a comparative analysis of the impact that the population residential areas have on the economic and social activity from Romania.
Gîdiu Valeria, Toader Valentin
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
VALUE ADDED TAX IN THE ECONOMIC CRISIS CONTEXT [PDF]
This article tries to present the major aspects concerning the value added tax in the context of economic crisis in European Union countries and Romania.
Cuceu Ionut +2 more
core
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source