Results 51 to 60 of about 10,656,742 (340)
HEQ volume 15 issue 4 Cover and Front matter [PDF]
, 1975 David Allnlendinger, Robert Church, Susan Houston, Sheldon Rothblatt, Vinlent Lannic, Katz York Ulliversity, Allan Stanley, Horlick New, York Ljniversity, Geraldine Jon~i~h, Cliftoro Ulliv, University Kaestle, Jviscollsin Of, H Paul +13 moreopenalex +1 more sourceA synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote +8 morewiley +1 more sourceRCE volume 15 issue 171 Cover and Front matter [PDF]
, 1975 Mr Martin, Mr Pictet, Mr Huber, Mr Bachmann, Mrs Denise Bindschedler-Robert, Mr Jacques, F De Rougemont, Mr Gallopin, Mr Jucker, Mr Victor, H Umbricht, Mr Micheli, Mr Etienne, Mr Middendorp, Mrs Marion, Mr Peter Tschudi, Mr Huguenin, Mr Gottfried, Dirk J. A. Smit, Mr Burckhardt, Mr Fleiner, Mr Alexandre Hay, Mr Cheneviere, Lucie Odier, Messrs Guillaume Bordier, Paul Carry, Mrs Marguerite Gautier-Van Berchem, Messrs Graedel, Edouard De Haller, Rodolfo Olgiati, Max Petitpierre, Paul Ruegger, Diètrich Schindler, Frédéric Siordet, Alfredo Executive Board, Mr Roger Gallopin, Etienne Gilbert, Ulrich Middendorp, Mr Jean, Pictet Mr, David Gottfried, Mr Smit, Micheli +42 moreopenalex +1 more sourceAdaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch +16 morewiley +1 more sourceEditorial Volume 15 Issue 1 2024
Student SuccessIn 2024 the Journal publishes its 15th volume, a significant achievement for a non-commercial open access publication.
The Journal has evolved significantly in recent years and submissions continue to increase in number and quality.Karen Nelson, Tracy Creaghdoaj +1 more sourcePatient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert +16 morewiley +1 more sourceAEQ volume 15 issue 2 Cover and Front matter [PDF]
, 1964 A B A L L A N T Y N E, C H A Y N E C O N S T A N T, F€ Ae, F€ Ae, Hon Ae, F€ Ae, F€ Ae, G Sir, M E O F F R E Y T A Y L O R, Malcolm C. Pike, A Ae, Mr Keith-Lucas, D Kuckbmann, Mr Mais, Roger G. Owen, Mr Pankhurst, Mr Pearcby, John Thwaites, G Batchelo, Mr Faoe, Walter Howarth, Julian R. Jones, L. Preston, J Squire, P. I. Temple, Mr Bryant, Mr Gates, Mr Lee, Mr Morgan, Mr Helicopters, Mr Bennett, Mr Brett, Mr Fatrhurjt, Gerhard Hafner, Capt Hblop, Instruments Liptrot, Gernld Sir, Georoe Gardner, Charles J. Hudson, Mr Jaques, Mr Meredith, Mr Bookman, Mr Clarkson, Mr Clifton, Mr Gardner, Mr Knowler, Mr Pollicutt, Ann Russell, Mr Stafford, Mr Stephens, Radar Mr, Mr Atherton, Robert M. Gates, A Rose, Robert Uttley, K Beroin, Alton Barbour, Mr Sound, Mr Makinson, Mr Greatrex, Mr Baxter, Mr Cleaver Sir, A Roy Fedden, Stanford B. Hooker, Mr Howell, Mr Lindsey, Mr Lloyd, E Morley, Mr Moult, Mr Mum, Mr Ntxon, Mr Owner, Mr Pearson, Mr Campbell, Orde Mr, Mr Masbfield, Mr Rows, Mr Shenstonb, Mr Bingham, Mr Clothier, Mr Conway Sir, George Dowty, Mr Graham, Mr Holland, Mr Daves, Mr Newman, M S Yates, Mr Duddy, Mr Hufton, Mr Stevens, Mr Aroyris, Angus Atkinson, Mr Barrett, Mr Cox, Mr Hill, Col Howard, Mr Jessop, Mr Keen, D Kerry, Mr Leooett +99 moreopenalex +1 more sourceThe Cowl - v.29 - n.11 - Sep 15, 1976 [PDF]
, 1976 The Cowl - student newspaper of Providence College. Volume 29, Number 11 - September 15, 1976. 8 pages. Note: The volume number printed on the banner page of this issue (XXIX) duplicates the volume number for the 1966-67 academic ...core +1 more source
