Results 71 to 80 of about 10,656,742 (340)
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto +12 morewiley +1 more sourceAAQ volume 15 issue 4 part 1 Cover and Front matter [PDF]
, 1950 President, ; Secretary, George Quimby, Assistant Editors, ; Frederica De Laguna, ; Arctic, Robert Heizer, Pacific Coast, ; Paul Reiter, Waldo Southwest, Wedel, ; Plains, G Richard, William Morgan, William Ritchie, Gordon Haag, Middle Ekholm, Gordon America, South Willey, ; America, H Frank, J Roberts, Jesse Jennings, Paul Martin, Philip Phillips, Gordon Willey +25 moreopenalex +1 more sourceGlycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala +18 morewiley +1 more sourceReduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh +8 morewiley +1 more sourceEos, Transactions, American Geophysical Union Volume 90, Number 50, 15 December 2009 [PDF]
, 2009 Glenn Tootle, Paul Miller, Venkat Lakshmi, John Dracup, Anny Cazenave, John Geissman, Hassan Virji, Robert Van, M Lee, Roni Avissar, Roland Tectonophysics, John Ebel, Arlene Fiore, Michael Gooseff, Hydrology Jung-Fu, Afu Lin, Rock Physics, Xin-Zhong Liang, Global Environmental, Stephen Macko, Stefan Geomagnetism, Jerry Miller, Michael Poland, Paul Renne Volcanology, Petrology Geochemistry, J Jeffery, Rock Roberts Mineral, John Physics, Nonlinear Rundle, Geophysics, Susan Sakimoto, Sarah Paleoceanography, David Sibeck, Maribeth Stolzenburg, Jeffrey Welker Biogeosciences, Barbara Richman, Randy Showstack, Mohi Kumar, Ernie Tretkoff, Melissa Corso, Liz Castenson, Faith Ishii, Rebecca Mesfin, Brian Kelm, Valerie Bassett, Mari Sa Grotte, Carole Saylor, Y Aoki, S Onizawa, M Takeo, Y Aoki, T Ohminato, M Yamamoto, A Zollo, A Zollo, J Selker, L Thvenaz, H Huwald, A Mallet, W Luxemburg, N Van De Giesen, M Stejskal, J Zeman, M Westhoff, M Parlange +64 moreopenalex +1 more sourceIntein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar +9 morewiley +1 more source