Results 61 to 70 of about 15,468,962 (298)

Volume 19, 1975-1976

open access: yes, 1975
Series 26957 | District Court (Second District : Weber County) | Index to civil actions | Volume 19, 1975-1976This series contains civil case alphabetic indexes created by the Second District Court in Weber County to record the names of the parties ...
Metadata created by Gina Strack based on description by Jim Kichas.   +1 more
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Feuilles d'album. 19, Souvenir : op. 15 n° 19 : [pour piano à 4 mains] / M. Balutet ; [ill. par] H. Viollet

open access: yes, 1903
Titre uniforme : Balutet, Marguerite (1853-19..). Compositeur. [Souvenir. Piano (4 mains). Op.
Balutet, Marguerite (1853-19..). Compositeur
core  

LIPIcs, Volume 134, ECOOP'19, Complete Volume

open access: yes, 2019
LIPIcs, Volume 134, ECOOP'19, Complete ...
Donaldson, Alastair F.
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

LIPIcs, Volume 148, IPEC'19, Complete Volume

open access: yes, 2019
LIPIcs, Volume 148, IPEC'19, Complete ...
Jansen, Bart M. P., Telle, Jan Arne
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

LIPIcs, Volume 141, ITP'19, Complete Volume

open access: yes, 2019
LIPIcs, Volume 141, ITP'19, Complete ...
Harrison, John   +2 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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