Results 51 to 60 of about 2,773,173 (303)

LIPIcs, Volume 133, ECRTS'19, Complete Volume

, 2019
LIPIcs, Volume 133, ECRTS'19, Complete ...
Quinton, Sophie
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

OASIcs, Volume 74, SLATE'19, Complete Volume

, 2019
OASIcs, Volume 74, SLATE'19, Complete ...
Janoušek, Jan, Ferreira, Luís, Batista, Fernando, Rodrigues, Ricardo, Gonçalo Oliveira, Hugo, Coheur, Luísa   +5 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Volume 19: The Party Volume

Volume 19 marks a milestone in the BCT Superfluid Lattice Model programme — the point at which the framework crossed 225 published letters, 278+ predictions, and 26 provisional patents, all from three geometric inputs and zero free parameters. This volume collects letters spanning the full breadth of BCT territory: cosmological phase evolution ...
openaire   +3 more sources

OASIcs, Volume 72, WCET'19, Complete Volume

, 2019
OASIcs, Volume 72, WCET'19, Complete ...
Altmeyer, Sebastian
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

OASIcs, Volume 75, ATMOS'19, Complete Volume

, 2019
OASIcs, Volume 75, ATMOS'19, Complete ...
Cacchiani, Valentina, Marchetti-Spaccamela, Alberto   +1 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

LIPIcs, Volume 135, TQC'19, Complete Volume

, 2019
LIPIcs, Volume 135, TQC'19, Complete ...
Mančinska, Laura, van Dam, Wim
core   +1 more source