Results 51 to 60 of about 79,216,419 (300)
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
LIPIcs, Volume 134, ECOOP'19, Complete Volume
, 2019 LIPIcs, Volume 134, ECOOP'19, Complete ...
Donaldson, Alastair F.
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Identità Differenze Conflitti
, 2007 Volume collettaneo che raccoglie gli interventi e i contributi del Convegno "Identità Differenze Conflitti" tenutosi a Venezia nel settembre 2007 a conclusione del PRIN 2004 (resp. naz. e loc. prof. L. Ruggiu)
Mora, Francesco +4 more
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
LIPIcs, Volume 148, IPEC'19, Complete Volume
, 2019 LIPIcs, Volume 148, IPEC'19, Complete ...
Jansen, Bart M. P., Telle, Jan Arne
core +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
LIPIcs, Volume 141, ITP'19, Complete Volume
, 2019 LIPIcs, Volume 141, ITP'19, Complete ...
Harrison, John +2 more
core +1 more source
LIPIcs, Volume 145, APPROX/RANDOM'19, Complete Volume [PDF]
, 2019 LIPIcs, Volume 145, APPROX/RANDOM'19, Complete ...
Achlioptas, Dimitris, Végh, László A.
core +1 more source