Results 91 to 100 of about 23,692,773 (298)

Dagstuhl Reports, Volume 5, Issue 4, April 2015, Complete Issue

open access: yes, 2015
Dagstuhl Reports, Volume 5, Issue 4, April 2015, Complete ...

core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Dagstuhl Reports, Volume 7, Issue 4, April 2017, Complete Issue

open access: yes, 2018
Dagstuhl Reports, Volume 7, Issue 4, April 2017, Complete ...

core   +1 more source

Volume 25, Número 4

open access: yesNovos Cadernos NAEA, 2022
Novos Cadernos NAEA
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Dagstuhl Reports, Volume 4, Issue 3, March 2014, Complete Issue

open access: yes, 2014
Dagstuhl Reports, Volume 4, Issue 3, March 2014, Complete ...

core   +1 more source

Index to Series 4 Volume V

open access: yesBulletin of popular information - Arnold Arboretum, Harvard University, 1937
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +3 more sources

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