Results 71 to 80 of about 23,692,773 (298)
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
, 2007 Volume collettaneo che raccoglie gli interventi e i contributi del Convegno "Identità Differenze Conflitti" tenutosi a Venezia nel settembre 2007 a conclusione del PRIN 2004 (resp. naz. e loc. prof. L. Ruggiu)
Mora, Francesco +4 more
core
Dagstuhl Reports, Volume 2, Issue 4, April 2012, Complete Issue
, 2012 Dagstuhl Reports, Volume 2, Issue 4, April 2012, Complete ...
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Dagstuhl Reports, Volume 9, Issue 4, April 2019, Complete Issue
, 2019 Dagstuhl Reports, Volume 9, Issue 4, April 2019, Complete ...
core +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Dagstuhl Reports, Volume 4, Issue 2, February 2014, Complete Issue
, 2014 Dagstuhl Reports, Volume 4, Issue 2, February 2014, Complete ...
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Dagstuhl Reports, Volume 4, Issue 5, May 2014, Complete Issue
, 2014 Dagstuhl Reports, Volume 4, Issue 5, May 2014, Complete ...
core +1 more source