MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
To Chemistry Journal, 2019 On behalf of the Editorial Board, it is with great pride and sincere privilege that I am writing this message to present the volume 4 (2019) of the to chemistry journal.
Dr. Sumit Kumar
doaj
Erratum: This is a corrigendum to: Kumthekar et al, A multi-institutional phase II trial of bevacizumab for recurrent and refractory meningioma, Neuro-Oncology Advances, Volume 4, Issue 1, January-December 2022, vdac123, https://doi.org/10.1093/noajnl/vdac123. [PDF]
Neurooncol Adv, 2023 europepmc +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Advances in Polyhydroxyalkanoate (PHA) Production, Volume 4. [PDF]
Bioengineering (Basel)Koller M.
europepmc +1 more source
Erratum: Publisher Correction: npj Vaccines, volume 4. [PDF]
NPJ Vaccines, 2019 npj Vaccines.
europepmc +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Corrigendum to 'Cardiac Catheterization and Interventions in Pediatric Patients on ECMO: Analysis of the IMPACT Registry' [Journal of the Society for Cardiovascular Angiography & Interventions; Volume 4, Issue 3 (2025): 102570]. [PDF]
J Soc Cardiovasc Angiogr IntervMcLean KD +4 more
europepmc +1 more source