Results 81 to 90 of about 6,046,760 (380)

Impact of Cholesterol on Voids in Phospholipid Membranes

open access: yes, 2004
Free volume pockets or voids are important to many biological processes in cell membranes. Free volume fluctuations are a prerequisite for diffusion of lipids and other macromolecules in lipid bilayers.
Almeida   +43 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structure and Properties of High and Low Free Volume Polymers Studied by Molecular Dynamics Simulation

open access: yesComputation, 2019
Using molecular dynamics, a comparative study was performed of two pairs of glassy polymers, low permeability polyetherimides (PEIs) and highly permeable Si-containing polytricyclononenes.
Mikhail Mazo   +4 more
doaj   +1 more source

Analysis of Fiber Distribution and Volume Ratio of Unidirectional Composite for Micromodels [PDF]

open access: yesTransactions of the VŠB-Technical University of Ostrava, Mechanical Series, 2013
This work focuses on assessment of real fiber and matrix volume ratios of unidirectional fiber composites which will be used while designing corresponding micromodels.
Hana SRBOVÁ   +3 more
doaj   +1 more source

Solving the inverse problem of high numerical aperture focusing using vector Slepian harmonics and vector Slepian multipole fields

open access: yes, 2012
A technique using vector Slepian harmonics and multipole fields is presented for a general treatment of the inverse problem of high numerical aperture focusing.
Bokor   +22 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Characteristics of Pore Volume Distribution and Methane Adsorption on Shales

open access: yesAdsorption Science & Technology, 2015
Shale pore structure has an important effect upon shale-gas adsorption. In order to quantify their contribution to the total amount of adsorbed gas, we investigate the pore volume distribution on shale, coal, isolated kerogen, and clay samples using low ...
Rui Wang   +5 more
doaj   +1 more source

Moments of Wigner function and Renyi entropies at freeze-out

open access: yes, 2005
Relation between Renyi entropies and moments of the Wigner function, representing the quantum mechanical description of the M-particle semi-inclusive distribution at freeze-out, is investigated.
A. Bialas   +12 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

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