Results 91 to 100 of about 724,123 (268)

Mathematical Modeling of Liquid Slag Layer Fluctuation and Slag Droplets Entrainment in a Continuous Casting Mold Based on VOF-LES Method

open access: yesHigh Temperature Materials and Processes, 2017
The slag behaviors, directly relating with the qualities of the final cast products, are influenced by the transient surface flow of liquid steel in a continuous casting mold.
Zhao Peng   +3 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Enhanced 3D Turbulence Models Sensitivity Assessment Under Real Extreme Conditions: Case Study, Santa Catarina River, Mexico

open access: yesHydrology
This study compares enhanced turbulence models in a natural river channel 3D simulation under extreme hydrometeorological conditions. Using ANSYS Fluent 2024 R1 and the Volume of Fluid scheme, five RANS closures were evaluated: realizable k–ε ...
Mauricio De la Cruz-Ávila   +1 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

CLSVOF-DEM method for simulation of gas–liquid-particles dam-break multiphase flow

open access: yesEngineering Applications of Computational Fluid Mechanics
The simulation of gas–liquid-particles dam-break multiphase flow has long been a focal point and a significant challenge in many fields such as water conservancy, chemical engineering, and energy.
Wenkang Meng, Yikui Wang, Ruidong An
doaj   +1 more source

Evaluating Thera-101 as a Low-Volume Resuscitation Fluid in a Model of Polytrauma. [PDF]

open access: yesInt J Mol Sci, 2022
Shah JS   +10 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Viscous Models Comparison in Water Impact of Twin 2D Falling Wedges Simulation by Different Numerical Solvers

open access: yesInternational Journal of Maritime Technology, 2018
In this paper, symmetric water entry of twin wedges is investigated for deadrise angle of 30 degree. Three numerical simulation of a symmetric impact, considering rigid body dynamic equations of motion in two-phase flow is presented.
Mehdi Mahmoodi   +2 more
doaj  

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