Results 81 to 90 of about 2,017,978 (347)

Computer simulation of preflight blood volume reduction as a countermeasure to fluid shifts in space flight [PDF]

open access: yes
Fluid shifts in weightlessness may cause a central volume expansion, activating reflexes to reduce the blood volume. Computer simulation was used to test the hypothesis that preadaptation of the blood volume prior to exposure to weightlessness could ...
Charles, J. B.   +2 more
core   +1 more source

Aplication of Flotran CFD in ANSYS [PDF]

open access: yes, 2014
Simulation program ANSYS. The aerodynamic simulation with CFD (Computational Fluid Dynamics). Finite element method (FEM). Volume element method (VEM).
Palko, Milan
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Comparison of Flow over Broad Crested Weir in Laboratory and by a Numerical Method

open access: yesWasit Journal of Engineering Sciences, 2018
The main purpose of this study is to test the ability of competition fluid dynamic (CFD) model which (FLUENT) program to simulate the flow over broad crested weir with lower cost and lesser time.
Laith Hamdan Hawal, Thameen Nazar Nahi
doaj   +1 more source

Vortex sheets and diffeomorphism groupoids

open access: yes, 2018
In 1966 V.Arnold suggested a group-theoretic approach to ideal hydrodynamics in which the motion of an inviscid incompressible fluid is described as the geodesic flow of the right-invariant $L^2$-metric on the group of volume-preserving diffeomorphisms ...
Izosimov, Anton, Khesin, Boris
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Dynamics of a massive intruder in a homogeneously driven granular fluid

open access: yes, 2012
A massive intruder in a homogeneously driven granular fluid, in dilute configurations, performs a memory-less Brownian motion with drag and temperature simply related to the average density and temperature of the fluid.
Gradenigo, G.   +3 more
core   +3 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Numerical evaluation on the efficiency of the submerged horizontal plate type wave energy converter [PDF]

open access: yesFME Transactions, 2019
The high availability of energy within ocean waves is seen as an important and abundant alternative as a renewable energy source. This paper presents a numerical study of the submerged horizontal plate type wave energy converter, assessing its ...
Seibt Flávio Medeiros   +6 more
doaj  

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