Results 131 to 140 of about 2,180,608 (342)

Viscous Models Comparison in Water Impact of Twin 2D Falling Wedges Simulation by Different Numerical Solvers

open access: yesInternational Journal of Maritime Technology, 2018
In this paper, symmetric water entry of twin wedges is investigated for deadrise angle of 30 degree. Three numerical simulation of a symmetric impact, considering rigid body dynamic equations of motion in two-phase flow is presented.
Mehdi Mahmoodi   +2 more
doaj  

Numerical analysis of the liquid ejection due to the gaseous jet impact through computational fluid dynamics

open access: yesREM: International Engineering Journal
Metal droplets generated by an impinging jet, play an important role in metal refining processes, mainly in oxygen steelmaking, where the droplets are ejected into the slag phase.
Hiuller Castro Araújo   +2 more
doaj   +1 more source

Viscous numerical wave tank for Bragg resonance by cnoidal and Stokes waves

open access: yesEngineering Applications of Computational Fluid Mechanics, 2018
In this study, a quadtreeadaptive viscous numerical wave tank in which the free surface is resolved by the volume of fluid method is established to solve Bragg resonance caused by Stokes and cnoidal waves.
Jen-Yi Chang   +2 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Numerical Simulation and Experimental Investigation of Flow Over a Cylindrical Weir Considering the Influence of Roughness Using the Standard k-ε Model [PDF]

open access: yesمهندسی منابع آب, 2013
In terms of the nature of flow profile over weirs, cylindrical weirs are classified as short-crested weirs. Advantages of the cylindrical weir shape include the stable overflow pattern, the ease to pass floating debris, the simplicity of design compared ...
A. A, S. H
doaj  

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

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