Bidirectional effects of voluntary exercise on the expression of Bdnf isoforms in the hippocampus of Hatano rat strains displaying different activity levels. [PDF]
Brain‐derived neurotrophic factor has functional mRNA isoforms, whose expression is assumed to mediate the beneficial effects of exercise in neuropsychiatric disorders.
Chiba S +6 more
europepmc +2 more sources
Orexin neurons mediate temptation-resistant voluntary exercise. [PDF]
AbstractDespite the well-known health benefits of physical activity, many people underexercise; what drives the prioritization of exercise over alternative options is unclear. We developed a task that enabled us to study how mice freely and rapidly alternate between wheel running and other voluntary activities, such as eating palatable food.
Tesmer AL +6 more
europepmc +4 more sources
Voluntary exercise could reduce sperm malformations by improving hypothalamus-hypophysis-gonadal axis and kisspeptin/leptin signaling in type 2 diabetic rats [PDF]
Objective(s): Most male patients with type 2 diabetes mellitus (T2DM) experience infertility. It is well established that regular physical activity could alleviate diabetic infertility symptoms.
Uldouz Kharazi +4 more
doaj +1 more source
The Zebrafish (Danio rerio) as a Model for Studying Voluntary Physical Exercise and its Effects on Behavior and Metabolism [PDF]
The objective of this study was to develop a viable and low-cost model of voluntary physical exercise that could be applied to studies on metabolism and behavior.
Moises Silvestre de Azevedo Martins +4 more
doaj +1 more source
Volumetric muscle loss (VML) is associated with irreversibly impaired muscle function due to traumatic injury. Experimental approaches to treat VML include the delivery of basic fibroblast growth factor (bFGF) or rehabilitative exercise. The objective of
Caroline Hu +5 more
semanticscholar +1 more source
Voluntary Wheel Running Exercise Improves Aging-Induced Sarcopenia via Activation of Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1α/Fibronectin Type III Domain-Containing Protein 5/Adenosine Monophosphate-Activated Protein Kinase Signaling Pathway [PDF]
Purpose In this study, the protective effect of voluntary wheel running exercise on muscle loss and muscle weakness in gastrocnemius of old rats was investigated.
Young Jun Ko, Il-Gyu Ko
doaj +1 more source
Voluntary exercise improves spermatogenesis and testicular apoptosis in type 2 diabetic rats through alteration in oxidative stress and mir-34a/SIRT1/p53 pathway [PDF]
Objective(s): This research was designed to demonstrate the impact of voluntary exercise on sperm parameters including sperm count, morphology, motility, viability, testicular apoptosis, oxidative stress, and the mir-34a/SIRT1/p53 pathway in type 2 ...
Saber Ghaderpour +4 more
doaj +1 more source
Spontaneous physical activity down-regulates Pax7 in cancer cachexia [PDF]
Emerging evidence suggests that the muscle microenvironment plays a prominent role in cancer cachexia. We recently showed that NF-kB - induced Pax7 overexpression impairs the myogenic potential of muscle precursors in cachectic mice, suggesting that ...
Adamo, Sergio +7 more
core +13 more sources
Voluntary Exercise Increases Oligodendrogenesis in Spinal Cord [PDF]
Exercise has been shown to increase hippocampal neurogenesis, but the effects of exercise on oligodendrocyte generation have not yet been reported. In this study, we evaluated the hypothesis that voluntary exercise may affect neurogenesis, and more in particular, oligodendrogenesis in the thoracic segment of the intact spinal cord of adult nestin-GFP ...
W, Krityakiarana +8 more
openaire +2 more sources
Influence of voluntary exercise on hypothalamic norepinephrine [PDF]
We combined hypothalamic tissue and plasma determinations of norepinephrine, dihydroxyphenylalanine, and dihydroxyphenylglycol with measurements of abdominal fat in voluntary running rats to examine the relationship among exercise training, hypothalamic and sympathetic nervous function, and body fat stores.
G W, Lambert, I H, Jonsdottir
openaire +2 more sources

