Results 51 to 60 of about 21,138 (359)
Design and optimization of bionic Nautilus volute for a hydrodynamic retarder
To reduce the energy loss of volute and improve the emergency braking performance of hydrodynamic retarder under design condition, a bionic volute optimization design method is proposed based on the Nautilus shell.
Wei Wei +4 more
doaj +1 more source
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
The non-axisymmetric geometry structure of the volute leads to the uneven circumferential distribution of the flow field inside centrifugal compressors.
Ce YANG +6 more
doaj +1 more source
Rotordynamic Forces on Centrifugal Pump Impellers [PDF]
The asymmetric flow around an impeller in a volute exerts a force upon the impeller. To study the rotordynamic force on an impeller which is vibrating around its machine axis of rotation, the impeller, mounted on a dynamometer, is made to whirl in a ...
Acosta, A. J. +4 more
core
The Effect of Inlet Swirl on the Rotordynamic Shroud Forces in a Centrifugal Pump [PDF]
The role played by fluid forces in determining the rotordynamic stability of a centrifugal pump is gaining increasing attention. The present research investigates the contributions to the rotordynamic forces from the discharge-to-suction leakage flows ...
Acosta, A. J. +3 more
core +2 more sources
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Unsteady behaviours of a volute in turbocharger turbine under pulsating conditions
Turbochargers are currently in their prime utilization period, which pushes for performance enhancement from conventional turbochargers and more often than not revisiting its design methodology.
Mingyang Yang +5 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source

