Results 201 to 210 of about 602,787 (351)

KOH‐Activated Pinecone Biochar for Efficient Chloramphenicol Removal From Aqueous Solutions

open access: yesCleanMat, EarlyView.
Pinecone‐based biochar was synthesized through pyrolysis at 600°C and KOH activation at 800°C under an N2 atmosphere. This process yielded a microporous structure with a significantly enhanced surface area. The biochar was then utilized to remove chloramphenicol (CAP) from aqueous solutions.
Xiaoran He   +4 more
wiley   +1 more source

GDF15 Analogues Acting as GFRAL Ligands

open access: yesChemMedChem, EarlyView.
Considering the great importance of the GDF15/GRAL/RET signalling pathway, this review focuses on GDF15‐derived analogues able to act either as GFRAL agonists or antagonists, investigating their possible pharmacological applications in the treatment of GDF15‐related conditions, such as obesity and diabetes (agonist), or cancer‐induced nausea and ...
Andrea Di Santo   +8 more
wiley   +1 more source

Corrin Ring Modification in Peptide Drug Development – a Brief History of “Corrination”

open access: yesChemMedChem, EarlyView.
This review highlights the applications of vitamin B12 conjugation (“corrination”) to peptides in the field of peptide‐based therapeutics, focusing on improved physio‐chemical properties, targeted/localized drug delivery, and enhanced oral bioavailability.
Nancy Cham, Robert P. Doyle
wiley   +1 more source

New pyridobenothiazolone derivatives display nanomolar pan‐serotype anti‐DENV activity

open access: yesChemMedChem, Accepted Article.
Dengue virus (DENV) serotypes 1–4 are mosquito‐borne flaviviruses that are responsible for significant morbidity and mortality worldwide, particularly in tropical and subtropical regions. Although two vaccines have been approved, their unbalanced efficacy across serotypes poses potential risks for specific populations.
Tommaso Felicetti   +13 more
wiley   +1 more source

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