Results 71 to 80 of about 9,097,505 (214)

Hypoxia and hypercapnia elicit overlapping but distinct skeletal muscle toxicities

The Journal of Physiology, EarlyView.
Abstract figure legend Hypoxia and hypercapnia cause overlapping skeletal muscle phenotypes, including atrophy, change in myofibre metabolic profile and myogenic response to injury. Both signals operate via distinct cellular pathways. Abstract Skeletal muscle dysfunction is strongly associated with elevated mortality in acute and chronic pulmonary ...
Joseph Balnis, Ariel Jaitovich
wiley   +1 more source

Hypoxia‐inducible factor‐1a (HIF1a) as a context‐dependent integrator of metabolic stress in skeletal muscle

The Journal of Physiology, EarlyView.
Abstract figure legend Hypoxia‐inducible factor‐1a (HIF1a) integrates physiological and pathological inputs in skeletal muscle, including exercise, circadian timing, cytotoxins and disease. These inputs alter mitochondrial oxidative function, redox state, reactive oxygen species, and local oxygen availability, leading to intermittent or sustained HIF1a
Nicole Welch, Pugazhendhi Kannan, Seshu Vardhan Pothabathula, Annette Bellar, Abhishek A. Chakraborty, Saurabh Mishra, Srinivasan Dasarathy   +6 more
wiley   +1 more source

Combined Pancreatic Endocrine Tumor and Serous Cystadenoma

Journal of the Formosan Medical Association, 2009
Pancreatic serous cystadenomas account for 1–2% of all exocrine pancreatic tumors, and endocrine tumors account for 1–2% of all pancreatic neoplasms. The combination of pancreatic serous cystadenoma and endocrine tumor is even rarer.
Min-Shu Hsieh, Kao-Lang Liu, Yu-Wen Tien, Chia-Tung Shun   +3 more
doaj   +1 more source

MANAGEMENT OF RETINAL HEMANGIOBLASTOMA IN VON HIPPEL–LINDAU DISEASE [PDF]

, 2019
PurposeTo review the current state of diagnosis and management of retinal hemangioblastoma and retinal vascular proliferation arising from von Hippel-Lindau (VHL) disease.MethodsA review of the literature was performed.
Michael B. Gorin, Gorin, Michael B, Aronow, Mary E, Shields, Jerry, Krivosic, Valerie, Shields, Carol, Alain Gaudric, Henry E. Wiley, Emily Y. Chew, Mary E. Aronow, Gaudric, Alain, Carol Shields, Chew, Emily Y, Jerry Shields, Valerie Krivosic, Wiley, Henry E   +15 more
core   +1 more source

Optimal Hypoxia Mimetic Small Molecules for Enhancing Angiogenic Properties of Stem Cells From Human Exfoliated Deciduous Teeth

International Endodontic Journal, Volume 59, Issue 10, Page 2122-2142, October 2026.
ABSTRACT Aim Hypoxic preconditioning of cells holds promise for regenerative therapies, yet identifying effective and safe methods for clinical application remains challenging. We aimed to determine optimal hypoxia‐mimetic small molecules (SMs) that stabilize hypoxia‐inducible factor‐1α (HIF‐1α) and their dosages for hypoxic preconditioning in stem ...
Hong Wang, Jiawei Liu, Xintao Yang, Mohamad Koohi‐Moghadam, Shuting Gao, Yuanyuan Han, Dineshi Sewvandi Thalakiriyawa, James Kit Hon Tsoi, Yanqi Yang, Waruna Lakmal Dissanayaka   +9 more
wiley   +1 more source

Spinal Hemangioblastomas in Von Hippel-Lindau Disease Mimicking a Spinal Dural Arteriovenous Fistula

Global Spine Journal, 2014
Introduction Spinal hemangioblastomas (HBs) are rare tumors that are closely associated with a diagnosis of Von Hippel-Lindau disease (VHL). A tissue diagnosis is needed to make the diagnosis of HB because many other entities can present similarly, which
J. Kalyvas, S. Change
doaj   +1 more source

Von Hippel Lindau Disease

, 1976
Von Hippel Lindau Disease with a mini retinal tumor. Pair with R1_C4b. Anatomy: Retina. Pathology: Hemangioblastoma. Disease/Diagnosis: Von Hippel Lindau disease. Clinical: No visual symptoms. Imaging: Flourescien angiogram in R1_C4b.IC-E2ciii-von-hippel-
William F. Hoyt, MD
core  

Altitudinal Visual Field Defect as the Presenting Sign of a Brain Tumor: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Brain tumors present with symptoms depending on their type, location, and stage. Most cause visual field defects respecting vertical meridians. Compressive optic neuropathy may produce altitudinal defects, mimicking ischemic optic neuropathy.
Farid Shekarchian, Mehrdad Motamed Shariati, Mohammadreza Same’   +2 more
wiley   +1 more source

Cerebellar Hemangioblastoma and Von Hippel-Lindau Disease

Pediatric Neurology Briefs, 2002
Six pediatric patients with cerebellar hemangioblastoma were screened for germline or somatic mutations of the von Hippel-Landau gene, in a study at Stanford University Medical Center, Palo Alto, CA.
J. Gordon Millichap
doaj   +1 more source

Von Hippel Lindau Disease

, 1970
Von Hippel Lindau Disease. Retinal photograph showing small whitish hemangiomablastoma. Note the dilated arterial and venous channels entering and leaving the tumor. Anatomy: Retina. Pathology: Hemangioblastoma.
William F. Hoyt, MD
core