Results 91 to 100 of about 36,491 (170)

Von Willebrand disease [PDF]

Clinical Medicine, 2007
openaire   +3 more sources

An experimental comparison and user evaluation of three different dried plasma products

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Access to blood components in pre‐hospital bleeding resuscitation is challenging. Dried plasma is a logistically superior alternative, and new products are emerging. Therefore, we aimed to evaluate laboratory and practical differences in three differently produced dried plasma products.
Kristina Ehn, Gabriel Skallsjö, Birgitta Romlin, Göran Sandström, Per Sandgren, Agneta Wikman   +5 more
wiley   +1 more source

Women in space: A review of known physiological adaptations and health perspectives

Experimental Physiology, EarlyView.
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford, Danielle J. Carroll, Heather C. M. Allaway, Bonnie J. Dunbar, Aenor J. Sawyer   +4 more
wiley   +1 more source

Environmental modulators of vascular physiology and inflammation

Experimental Physiology, EarlyView.
Abstract Environmental factors play a crucial role in modulating vascular inflammation, contributing significantly to the development of atherosclerosis and cardiovascular disease. This review synthesizes current evidence on how various environmental exposures influence vascular function and inflammation, with a focus on pollutants such as particulate ...
Anusha N. Seneviratne, Anne Majumdar, Kalpana Surendranath, Mark R. Miller   +3 more
wiley   +1 more source

The RhoA guanine exchange factor ABR: a glucose‐sensitive mediator of actin reorganization in feto‐placental arterial endothelial cells altered by gestational diabetes mellitus

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of proposed relationship between hyperglycaemia, gestational diabetes mellitus (GDM), active BCR‐related (ABR), RhoA and actin organization of feto‐placental arterial endothelial cells (fpEC). Hyperglycaemia upregulates ABR, which in turn increases RhoA activation.
Silvija Tokic, Boris Novakovic, Barbara Leopold‐Posch, Magdalena Mühlberger, Denise Hoch, Jelena Lögl, Eva M. Bernhart, Richard Saffery, Gernot Desoye, Ursula Hiden   +9 more
wiley   +1 more source

Evidence for control of cerebral neurovascular function by circulating platelets in healthy older adults

The Journal of Physiology, EarlyView.
Abstract figure legend Epidemiological evidence suggests a link between dementia and cardiovascular health, including the regulation of platelets. To investigate this relationship, we examined how platelet reactivity relates to cerebral neurovascular function and systemic vascular reactivity in healthy older adults.
Gabriella M. K. Rossetti, Joanne L. Dunster, Aamir Sohail, Brendan Williams, Kiera M. Cox, Suzannah Rawlings, Elysia Jewett, Eleanor Benford, Julie A. Lovegrove, Jonathan M. Gibbins, Anastasia Christakou   +10 more
wiley   +1 more source

Optic Nerve Sheath Meningiomas in Children: Diagnostic Challenges Based on a Case Series

Pediatric Blood &Cancer, Volume 72, Issue 7, July 2025.
ABSTRACT The diagnosis of optic nerve sheath meningiomas (ONSM) in children and teenagers remains challenging despite advances in high‐quality imaging. We identified seven children diagnosed with ONSM in four tertiary paediatric oncology centres in the United Kingdom.
Deysha Ratnasingham, George Lawson, Harpreet Hyare, Sam Gurney, John Apps, Ian Reekie, Sucheta Vaidya, Carmen Soto, Kavitha Srivatsa, Jaroslaw Peregud‐Pogorzelski, Andrzej Brodkiewicz, Owase Jeelani, Mette Jorgensen, Sarita Depani, Darren Hargrave, Elwira Szychot   +15 more
wiley   +1 more source

Identification of a Novel Mutation in the SERPINE1 Gene Causing Clinical Hyperfibrinolysis in English Springer Spaniel Dogs

Journal of Veterinary Internal Medicine, Volume 39, Issue 4, July/August 2025.
ABSTRACT Background A 7‐month‐old female spayed English Springer Spaniel (ESS) was evaluated for spontaneous hemoperitoneum. Hyperfibrinolysis was identified on thromboelastography. Hypothesis/Objectives To identify a genetic mutation causing congenital hyperfibrinolysis in the proband and evaluate the prevalence of the mutation in the ESS breed ...
Kelley Kilpatrick, Jonah N. Cullen, Farah F. Almeer, LeeAnn Higgins, Todd Markowski, Marjory Brooks, Steven G. Friedenberg, Molly Racette   +7 more
wiley   +1 more source

A Novel Interaction of Staphylococcal Protein A With Human Fibronectin and Its Implications in Host Cell Adhesion

The FASEB Journal, Volume 39, Issue 11, 15 June 2025.
Through this study, we discovered and characterized a previously undescribed interaction between Staphylococcal protein A (SpA) and human fibronectin. We also present data that suggest a potential mechanism for SpA's contribution to bacterial adhesion to host cells, opening to potential new strategies to fight S. aureus infections.
S. Camaione, W. Pansegrau, F. Concetti, M. Del Vecchio, L. Dello Iacono, I. Ferlenghi, A. G. O. Manetti, L. Manzi, N. Norais, A. Pellegrini, S. Savino, I. Margarit, G. Pietrocola   +12 more
wiley   +1 more source

Topics of Interest in Women With Myeloproliferative Neoplasms

American Journal of Hematology, Volume 100, Issue S4, Page 74-87, June 2025.
Women with MPN: life‐cycle phases, specific risks, and influencing factors. ABSTRACT Overview Sex and gender have emerged as central modifiers of disease biology, phenotype, and clinical outcomes in myeloproliferative neoplasms (MPNs). This review will uniquely highlight issues affecting women with MPN and articulate their relevant determinants ...
Natasha Szuber, Paola Guglielmelli, Naseema Gangat   +2 more
wiley   +1 more source