Albumin Restores Endothelial Cell Mitochondrial Morphology in Patients With Decompensated Cirrhosis
ABSTRACT Background & Aims Endothelial cell (EC) activation is a critical driver of disease progression in cirrhosis, contributing to acute decompensation (AD) and acute‐on‐chronic liver failure (ACLF). Although human albumin administration improves EC function in cirrhotic patients with hypoalbuminemia, its direct effects on ECs remain unclear.
Susan E. Fischer +5 more
wiley +1 more source
Immune Thrombocytopenia and Type 1 von Willebrand Disease in a Patient With a Femoral Fracture: A Case Report. [PDF]
Ferreira A, Roberto A.
europepmc +1 more source
Dried plasma retains hemostatic function and thermal stability during Arctic military operations
Abstract Background Dried plasma offers a practical alternative for remote damage control resuscitation, providing hemostatic support and volume replacement. The Arctic presents challenges that necessitate the need for blood‐based resuscitation to extend the “golden hour.” To address this, we evaluated the hemostatic and thermal stability of dried ...
Kanwal Singh +17 more
wiley +1 more source
Real-word evidence on healthcare resource use and associated costs in on-demand users of replacement therapies in von Willebrand disease in France: the FORvWARD study. [PDF]
Polack B +12 more
europepmc +1 more source
Abstract Background ABO blood groups may be associated with increased risk for several diseases including cardiovascular diseases (CVDs), particularly coronary heart disease (CHD). The role of other significant blood group systems, such as RhD and RhCE, has not been extensively investigated.
Surendra Karki +4 more
wiley +1 more source
Characteristics and posttransplant outcomes of patients with congenital and acquired von Willebrand disease and hemophilia A and with renal transplants. [PDF]
Chang IW, Truman M, Yee C, Padrnos L.
europepmc +1 more source
Abstract Background Therapeutic plasma exchange (TPE) using exclusively albumin replacement fluid depletes coagulation factors, particularly fibrinogen, and concerns about performing multiple consecutive daily procedures due to iatrogenic bleeding exist. Fibrinogen testing to guide bleeding risk stratification is vague.
Jay S. Raval +7 more
wiley +1 more source
Rewriting the script: gene therapy and genome editing for von Willebrand Disease. [PDF]
Barraclough A +8 more
europepmc +1 more source
Type 3 von Willebrand disease in Ethiopia: a comprehensive literature review and report of the first three cases. [PDF]
Arega G +7 more
europepmc +1 more source
Platelet clotting defects in severe trauma identified by a whole blood microfluidic assay
Abstract Background Hemorrhage is the leading cause of preventable death in severe trauma, with primary hemostasis relying on platelet‐rich clot formation under high shear flow. This study quantifies the incidence, severity, and heterogeneity of platelet dysfunction in Level I trauma patients.
Gian Rivera Crespo +4 more
wiley +1 more source

