Results 61 to 70 of about 36,491 (170)

Different effects of oral and transdermal hormone replacement therapies on Factor IX, APC resistance, t-PA, PAI and C- reactive protein - a cross-sectional population survey [PDF]

, 2001
The effects of hormone replacement therapy (HRT) on thrombosis risk, thrombotic variables, and the inflammatory marker C- reactive protein (CRP) may vary by route of administration (oral versus transdermal).
Lowe, G.D.O., McConnachie, A., O'Reilly, D.S., Rumley, A., Upton, M.N., Watt, G.C.M.   +5 more
core  

Platelets: New bricks in the building of neutrophil extracellular traps [PDF]

, 2016
In addition to being key elements in hemostasis and thrombosis, platelets have an important role in the inflammatory and innate immune response. This activity is associated with their capability to recognize pathogens through the expression of toll-like ...
Carestia, Agostina, Kaufman, Tomás, Schattner, Mirta Ana   +2 more
core   +1 more source

In Vitro Comparison of Device‐Induced Hemolysis, Platelet Defects, and von Willebrand Factor Degradation Between the HeartMate 2 and HeartMate 3 Pumps

Artificial Organs, EarlyView.
This in vitro comparative study demonstrated that the HeartMate 3 pump has a superior overall hemocompatibility profile to the HeartMate 2 pump, underscoring the advantages of the maglev centrifugal pump design compared to the axial pump design. ABSTRACT Background Left ventricular assist devices (LVADs) have been utilized to maintain the circulatory ...
John Vandenberge, Dong Han, Wenji Sun, Shigang Wang, Douglas Tran, Nancy Kim, Kiersten Clark, Randy Perez, Bartley P. Griffith, Zhongjun J. Wu   +9 more
wiley   +1 more source

Von Willebrand Disease in the Netherlands [PDF]

, 2011
Based on previous epidemiologic studies it is estimated that in the Netherlands the referral based prevalence of moderate to severe von Willebrand disease (VWD) is approximately 1 in 10,000 (1650 patients). This does not include patients with mild type 1
Wee, E.M. (Eva) de
core  

Menstrual suppression to decrease intrauterine device expulsion in adolescents with inherited bleeding disorders

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 421-423, April 2025.
Peter H. Cygan, Kelly M. Kons, Megan H. Fiorillo, Tonya S. Wright   +3 more
wiley   +1 more source

How we manage immune‐mediated thrombotic thrombocytopenic purpura after rituximab failure or intolerance

British Journal of Haematology, EarlyView.
The use of rituximab as a pre‐emptive treatment in immune‐mediated thrombotic thrombocytopenic purpura (iTTP) is the current standard of care. However, for patients refractory to rituximab or for those with contraindication, further treatment guidelines are scarce.
Julia Weisinger, Jehane Fadlallah, Bérangère Joly, Agnès Veyradier, Paul Coppo   +4 more
wiley   +1 more source

Role of the RAB27/SYTL Axis in Tumor Microenvironment Construction

Cancer Science, EarlyView.
This review focuses on the role of the RAB27/SYTL axis in various cancer types associated with tumor microenvironment modifications. The importance of this pathway and the potential therapeutic strategies targeting vesicle production for the treatment of cancer are also discussed.
Miwa Tanaka, Takuro Nakamura
wiley   +1 more source

The Interaction Between Vasculogenic Mimicry and the Immune System: Mechanistic Insights and Dual Exploration in Cancer Therapy

Cell Proliferation, EarlyView.
VM is a novel form of angiogenesis discovered in many malignant tumours in recent years. And the well‐known immune response and related immune cells play different regulatory roles in the formation of VM. ABSTRACT Vasculogenic mimicry (VM) represents a novel form of angiogenesis discovered in numerous malignant tumours in recent years.
Shutong Liu, Mei Kang, Yuqing Ren, Yuyuan Zhang, Yuhao Ba, Jinhai Deng, Peng Luo, Quan Cheng, Hui Xu, Siyuan Weng, Anning Zuo, Xinwei Han, Zaoqu Liu, Teng Pan, Li Gao   +14 more
wiley   +1 more source

Contrasting Approaches in the Implementation of GRADE Methodology in Guidelines for Haemophilia and Von Willebrand Disease

Haemophilia, EarlyView.
ABSTRACT Introduction The 2024 ISTH clinical practice guideline (CPG) for treatment of congenital haemophilia, the NBDF‐McMaster Guideline on Care Models for Haemophilia Management, and ASH ISTH NBDF WFH guidelines on the diagnosis and management of VWD all utilised GRADE methodology.
Mark W. Skinner, Manuela Albisetti, Jesús Ardila, Jan Astermark, Jan Blatny, Manuel Carcao, Pratima Chowdary, Nathan T. Connell, Miguel Crato, Yesim Dargaud, Roseline d'Oiron, Amy L. Dunn, Miguel A. Escobar, Carmen Escuriola‐Ettingshausen, Emna Gouider, Annie Harroche, Cedric Hermans, Victor Jimenez‐Yuste, Radoslaw Kaczmarek, Gili Kenet, Liane Khoo, Robert Klamroth, Florian Langer, David Lillicrap, Johnny Mahlangu, Christoph Male, Tadashi Matsushita, Sandrine Meunier, Wolfgang Miesbach, Beatrice Nolan, Johannes Oldenburg, Brian O'Mahony, Margareth Ozelo, Glenn F. Pierce, Gloria Ramos, Michael Recht, Olivia Romero‐Lux, Dawn Rotellini, Rita C. Santoro, Tammuella C. Singleton, Alok Srivastava, Sophie Susen, Kate Talks, Huyen Tran, Leonard A. Valentino, Jerzy Windyga, Renchi Yang, Maria Elisa Mancuso, also on behalf of AICE, AHAD‐AP, AHCDC, ATHN, CLAHT, EHC, French CRH & MHEMO, HTCCNC, NBDF, PEDNET, UKHCDO, WFH   +59 more
wiley   +1 more source

Clinical, Phenotypic and Genotypic Characteristics of Von Willebrand Disease in Afro‐Caribbeans: Results From a Study in Martinique Island, French West Indies

Haemophilia, EarlyView.
ABSTRACT Background Several cohort studies have investigated the molecular basis of von Willebrand disease (VWD); very few have focused on the Afro‐Caribbean population. Objectives To determine the genotypic and phenotypic characterization of VWD in a large cohort of Afro‐Caribbean patients living in Martinique.
Marie‐Daniéla Dubois, Olivier Nicolas Pierre‐Louis, Serge Pierre‐Louis, Pierre Boisseau, Cécile V. Denis, Annabelle Dupont, Jenny Goudemand, Caterina Casari, Emmanuelle Jeanpierre, Christophe Zawadzki, Béatrice Ferrey, Johalène Rabout, Pascal Fuseau, Emelyne Chonville, Franck Michel, Marie‐Nadiège Yerro, Yves Gruel, Olivier Christophe, Peter J. Lenting, Eustase Janky, Sophie Susen, Rémi Neviere   +21 more
wiley   +1 more source