Results 61 to 70 of about 151,232 (337)

The VWF binding aptamer rondoraptivon pegol increases platelet counts and VWF/FVIII in type 2B von Willebrand disease [PDF]

, 2022
Cihan Ay, Ingrid Pabinger, Katarina D. Kovacevic, Georg Gelbenegger, Christian Schörgenhofer, Peter Quehenberger, Petra Jilma‐Stohlawetz, Raute Sunder‐Plaßmann, James C. Gilbert, Shuhao Zhu, Bernd Jilma, Ulla Derhaschnig   +11 more
openalex   +1 more source

Revisiting Incomplete Tissue‐Level Reperfusion Following Successful Thrombectomy for Acute Ischemic Stroke

Annals of Neurology, EarlyView.
Among patients with acute ischemic stroke achieving successful large vessel recanalization (defined as expanded Thrombolysis in Cerebral Infarction [eTICI ≥2b]), incomplete tissue‐level reperfusion, distinct from visually identifiable distal occlusion on digital‐subtraction angiography, remains a significant challenge.
Yue Qiao, Adrien Ter Schiphorst, Yi Xu, Jean‐Claude Baron, Wenbo Zhao   +4 more
wiley   +1 more source

von Willebrand Disease: The diagnosis and management of this bleeding disorder

Medical Journal of Babylon, 2020
von Willebrand disease (vWD) is one of the most common bleeding disorders, first described by Erik von Willebrand in the Aland Islands. It occurs as a result of decreased or abnormal von Willebrand factor (vWF), a factor that is needed in the process of ...
Basim A. Abd, Nawrass J Al-Salihi
doaj   +1 more source

Clot Composition Profiling in Large Vessel Occlusion Stroke Via Radiomics

Annals of Neurology, EarlyView.
Objective Clot composition may offer insights into the mechanism of ischemic stroke. Radiomics, a noninvasive imaging technique, enables tissue characterization through radiomic features (RFs). We aimed to evaluate clot composition using radiomics on non‐contrast computed tomography (NCCT).
Andres Gudino, Elena Sagues, Carlos Dier, Diego Ojeda, Samantha Saenz‐Hinojosa, Sebastian Sanchez, Ariel Vargas, Linder Wendt, Maria Belen Torres, Emily Garces, Alex Hanson, Navami Shenoy, Connor Aamot, Susan A. Walsh, Anil K. Chauhan, Gowri Anil‐Peethambar, Santiago Ortega‐Gutierrez, Jay Kinariwala, Mohamed Elshikh, Amir Shaban, Enrique C. Leira, Osorio Lopes Abath Neto, Malik Ghannam, Edgar A. Samaniego   +23 more
wiley   +1 more source

Recombinant von Willebrand Factor for Pediatric Patient with von Willebrand Disease: First Report in Korea

Clinical Pediatric Hematology-Oncology, 2021
von Willebrand disease (VWD) is the most common hereditary bleeding disorder. The treatment of VWD consists mainly of desmopressin and plasma-derived von Willebrand factor (pd-VWF) concentrate.
Seoin Kim, Young Shil Park
doaj   +1 more source

Biomarkers of Lupus Nephritis Histopathology: Where Do We Stand?

Arthritis &Rheumatology, EarlyView.
Objective Lupus nephritis (LN) is characterized by a variable disease course, necessitating continuous monitoring. There is an urgent need to identify noninvasive biomarkers. By reviewing and critically assessing the quality of existing studies on LN biomarkers correlating with histopathology, we here explore the challenges in promoting their use in ...
Valentina Querin, Leonardo Palazzo, Agnes B. Fogo, Mark Haas, David R. W. Jayne, Liz Lightstone, Brad H. Rovin, Surya V. Seshan, Augusto Vaglio, Ioannis Parodis, Ingeborg M. Bajema, for the Lupus Nephritis Classification Steering Committee   +11 more
wiley   +1 more source

Diagnostic Value of Measuring Platelet Von Willebrand Factor in Von Willebrand Disease. [PDF]

PLoS ONE, 2016
Von Willebrand disease (VWD) may be caused by an impaired von Willebrand factor (VWF) synthesis, its increased clearance or abnormal function, or combinations of these factors.
Alessandra Casonato, Maria Grazia Cattini, Viviana Daidone, Elena Pontara, Antonella Bertomoro, Paolo Prandoni   +5 more
doaj   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Patient with Dyspnea, Dysphagia and Menorrhagia: Plummer — Vinson Syndrome Against the Background of von Willebrand Disease

Российский журнал гастроэнтерологии, гепатологии, колопроктологии
Aim: to present a clinical observation of a patient with Plummer — Vinson syndrome against the background of von Willebrand disease.Key points. A 40-years-old woman presented to the hematology department of our hospital with fatigue, dizziness, dyspnea ...
A. A. Saenko, A. I. Dolgushina, O. V. Korobitsyna, E. R. Olevskaya, A. O. Khikhlova, A. S. Kuznezowa, V. V. Genkel, G. M. Khusainova   +7 more
doaj   +1 more source

CardiLect: A combined cross‐species lectin histochemistry protocol for the automated analysis of cardiac remodelling

ESC Heart Failure, Volume 12, Issue 2, Page 1398-1415, April 2025.
Abstract Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as immunohistochemistry.
Tamás G. Gergely, Tamás Kovács, Andrea Kovács, Viktória E. Tóth, Nabil V. Sayour, Gábor M. Mórotz, Csenger Kovácsházi, Gábor B. Brenner, Zsófia Onódi, Balázs Enyedi, Domokos Máthé, Przemyslaw Leszek, Zoltán Giricz, Péter Ferdinandy, Zoltán V. Varga   +14 more
wiley   +1 more source