Quantitative Systems Pharmacology Modeling of Platelet Responses to Recombinant ADAMTS13 in Patients With Congenital Thrombotic Thrombocytopenic Purpura. [PDF]
CPT Pharmacometrics Syst PharmacolABSTRACT Congenital thrombotic thrombocytopenic purpura (cTTP) is an ultra‐rare, life‐threatening thrombotic microangiopathy caused by a severe inherited deficiency of ADAMTS13, a von Willebrand factor (VWF) cleaving enzyme. Inadequate clinical endpoint data often make it challenging to statistically power clinical trials in ultra‐rare diseases ...
McBride C +8 more
europepmc +2 more sources
Identification of two mutations (Arg611Cys and Arg611His) in the A1 loop of von Willebrand factor (vWF) responsible for type 2 von Willebrand disease with decreased platelet-dependent function of vWF [see comments] [PDF]
, 1995 Lysiane Hilbert +2 more
openalex +1 more source
Coronary Spasm Due to Pulsed Field Ablation: A State‐of‐the‐Art Review
Pacing and Clinical Electrophysiology, EarlyView.ABSTRACT With the ever‐growing population of patients undergoing cardiac ablation with pulsed electric fields, there is a need to understand secondary effects from the therapy. Coronary artery spasm is one such effect that has recently emerged as the subject of further investigation in electrophysiology literature.
David A. Ramirez +3 more
wiley +1 more source
CLINICAL CONTRIBUTION TO VON WILLEBRAND DISEASE IN CHILDREN AFFECTED BY PATHOLOGIES WITH ENDOTHELIAL DAMAGE IN PRESENCE OF BLEEDING MANIFESTATIONS 187 [PDF]
, 1997 N Violante +6 more
openalex +1 more source
Successful Treatment of Severe Purpura Fulminans With Anakinra
Pediatric Dermatology, EarlyView.ABSTRACT Purpura fulminans (PF) is a rare, often fatal pediatric condition characterized by intravascular thrombosis and hemorrhagic infarction of the skin. A timely diagnosis and treatment are paramount to prevent the involvement of internal organs, causing disseminated intravascular coagulation and gangrene of the extremities.
Francesco Zulian +4 more
wiley +1 more source
Risk assessment of pARDS in severe pneumonia patients based on lung injury prediction scores and serum biomarkers. [PDF]
Sci RepQiao J, Feng Y, Cui C, Zou L, Huang X.
europepmc +1 more source
Congenital infiltrating lipoma of the upper limb in a patient with von Willebrand disease [PDF]
, 2000 Jose María Lasso +4 more
openalex +1 more source
Chronic Morel‐Lavallée Lesion in a Pediatric Competitive Dancer: A Case Report and Literature Review
Pediatric Dermatology, EarlyView.ABSTRACT Morel‐Lavallée lesions (MLLs) are rare internal degloving injuries resulting from shearing trauma, with few reported cases in the pediatric population. We present the case of a 16‐year‐old female competitive dancer with persistent right knee pain, skin atrophy, and ecchymosis after trauma sustained during a national dance competition, with MRI
Cameron Coakes +3 more
wiley +1 more source
Von Willebrand factor propeptide as a marker of disease activity in systemic sclerosis (scleroderma) [PDF]
, 2001 A Scheja +6 more
openalex +1 more source