Results 251 to 260 of about 58,549 (319)

Survey of functional Mendelian variants in New Zealand Huntaway and Heading dog breeds

Animal Genetics, Volume 56, Issue 5, October 2025.
Abstract New Zealand (NZ) Huntaway and Heading dogs are working breeds that play active roles on farms across NZ. While these breeds are common in NZ, they are not well‐known elsewhere, and little is understood about their genetic make‐up. Here, we used whole genome sequencing to provide a comprehensive genomic view of 249 working dogs. As first use of
Florence Smith, Thomas Lopdell, Melissa Stephen, Millicent Henry, Keren Dittmer, Hayley Hunt, Nick Sneddon, Liam Williams, Jack Rolfe, Dorian Garrick, Mathew D. Littlejohn   +10 more
wiley   +1 more source

Heyde syndrome: Experiences with the use of semiautomatic vWF multimer analysis for diagnosis and TAVI for treatment - case report. [PDF]

Medicine (Baltimore)
Focko B, Miertová Z, Škorňová I, Hudec M, Péč MJ, Jurica J, Cingel M, Bolek T, Sokol J, Poliačiková P, Mokáň M, Samoš M.   +11 more
europepmc   +1 more source

Micro‐Embolic Events and Their Clearing in the Brain. A Narrative Review

Acta Physiologica, Volume 241, Issue 10, October 2025.
ABSTRACT Background The cerebral circulation is continuously challenged by intravascular micrometer‐sized particles that become trapped microvascular‐emboli. These particles may include micro‐thrombi, stiffened erythrocytes, and leukocytes, while also fat particles, air, and microplastics may cause microvascular embolism. Review Scope In this narrative
Kevin Mol, Inge A. Mulder, Ed van Bavel
wiley   +1 more source

Rewriting the script: gene therapy and genome editing for von Willebrand Disease. [PDF]

Front Genome Ed
Barraclough A, Bär I, van Duijl T, Fijnvandraat K, Eikenboom JCJ, Leebeek FWG, Bierings R, Voorberg J, Trasanidou D.   +8 more
europepmc   +1 more source

Polypharmacy in mice disrupts left ventricular function and structure and promotes proteome reorganisation in an age‐ and sex‐specific fashion

British Journal of Pharmacology, Volume 182, Issue 19, Page 4625-4646, October 2025.
Background and Purpose Most older people use polypharmacy (≥5 medications), particularly those with cardiovascular disease. The effects of polypharmacy on the cardiovascular system are not well described. We examined the effect of a chronic polypharmacy regimen on left ventricular (LV) function, structure and proteome in young and old mice of both ...
Trang Tran, Kevin Winardi, Scott P. Levick, Alexander Widiapradja, Gizem Gemikonakli, Susan E. Howlett, Matthew J. McKay, Mark P. Molloy, John Mach, Sarah N. Hilmer   +9 more
wiley   +1 more source

Refractory anaemia in a patient with end‐stage heart failure secondary to aortic stenosis

ESC Heart Failure, Volume 12, Issue 5, Page 3766-3770, October 2025.
Jiayu Liang, Suxin Luo, Bi Huang
wiley   +1 more source

Role of Tie‐2 Axis in Sepsis: A Potential Therapeutic Target

Journal of Cellular and Molecular Medicine, Volume 29, Issue 20, October 2025.
ABSTRACT The angiopoietins (Angs)–Tie‐2 axis initiates signalling pathways that modulate vascular stability and angiogenesis and plays an important role in a variety of physiological and pathological processes, including inflammation, wound healing and cancer, by regulating endothelial cell proliferation, survival, migration, invasion and/or ...
Jun Feng, Junhui Liu, Xiaoyan Wu, Junshuai Wang   +3 more
wiley   +1 more source

Thromboembolic Risk and High Prothrombotic Factors in Childhood Acute Lymphoblastic Leukemia with Ischemic Stroke: A Literature Review of Personalized and Institutional Approaches to Prophylaxis. [PDF]

J Pers Med
Malczewska M, Dudkiewicz E, Zawitkowska J, Lejman M.   +3 more
europepmc   +1 more source

Medical haematology trial eligibility and the Duffy null‐associated neutrophil count: A cross‐sectional study

HemaSphere, Volume 9, Issue 10, October 2025.
Olga Tsiamita, Laura Aiken, Mohsin Badat, Gill Lowe, Funmi Oyesanya, Sonia Wolf, Lauren E. Merz, Andrew Hantel, Stephen P. Hibbs   +8 more
wiley   +1 more source

Diagnostic and Clinical Implications of High Spleen‐To‐Liver Stiffness Ratio in MASH—A Prospective, Comparative Study

Liver International, Volume 45, Issue 10, October 2025.
ABSTRACT Background Liver stiffness measurement (LSM) and spleen stiffness measurement (SSM) represent non‐invasive surrogates of portal hypertension (PH) that both correlate with hepatic venous pressure gradient (HVPG). SSM may overcome limitations of HVPG and LSM in detecting presinusoidal PH components.
Christian Sebesta, Mathias Jachs, Lukas Hartl, Michael Schwarz, Lorenz Balcar, Benedikt S. Hofer, Nina Dominik, Georg Kramer, Bernhard Scheiner, Albert F. Stättermayer, Benedikt Simbrunner, Till Schöchtner, Friedrich Haimberger, Nicolas Balutsch, Michael Trauner, Mattias Mandorfer, Thomas Reiberger, David J. M. Bauer   +17 more
wiley   +1 more source