Results 191 to 200 of about 102,475 (311)

Metformin as a Multifaceted Therapeutic Agent for Gastrointestinal Diseases: Mechanisms, Clinical Efficacy, and Future Directions

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT The high prevalence of gastrointestinal (GI) diseases and their significant impact on the quality of life require new therapeutic strategies. The development of novel therapeutic strategies should prioritize targeting the fundamental pathophysiological mechanisms underlying these diseases, including inflammation, cellular proliferation, and ...
Sayedeh Azimeh Hosseini   +7 more
wiley   +1 more source

Role of plasma Von-Willebrand factor in children with chronic liver diseases. [PDF]

open access: yesEur J Pediatr
Behairy OGA   +5 more
europepmc   +1 more source

Nanobodies: A Promising Toolkit for Diagnostic Applications

open access: yesSmartMat, Volume 7, Issue 3, June 2026.
This review focuses on camelid‐derived nanobodies (VHHs) and explains how their small size and high stability support robust diagnostic design. Applications across ELISA, lateral flow assays, and PET/SPECT imaging are summarized, along with clinical progress such as caplacizumab.
Wei Wu   +11 more
wiley   +1 more source

Von Willebrand Factor Multimers in Aortic Stenosis Surgery: Dynamics and Disease Correlation. [PDF]

open access: yesJ Atheroscler Thromb
Tachioka S   +11 more
europepmc   +1 more source

Estetrol‐based combined oral contraceptives: A systematic review of clinical outcomes

open access: yesActa Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 6, Page 983-998, June 2026.
This systematic review summarizes clinical outcomes of estetrol‐containing combined oral contraceptives, showing reliable contraceptive efficacy, predictable bleeding patterns, improved well‐being, and a favorable hemostatic and metabolic profile, suggesting a promising and potentially safer alternative to ethinylestradiol‐based formulations.
Mathilde Råberg   +3 more
wiley   +1 more source

Common Hematologic Emergencies—Acute Promyelocytic Leukemia and Microangiopathic Hemolytic Anemias—A Pivotal Role of Clinical Laboratory

open access: yesInternational Journal of Laboratory Hematology, Volume 48, Issue 3, Page 521-530, June 2026.
ABSTRACT Hematologic emergencies are urgent health conditions which result in significant mortality and morbidity unless timely therapeutic measures are taken. Therapeutic success depends on their timely and accurate recognition by hematology laboratory services.
Ganna Shestakova   +2 more
wiley   +1 more source

Intraindividual variability of von Willebrand factor and the need for repeated testing. [PDF]

open access: yesRes Pract Thromb Haemost
Kirkeby MH   +3 more
europepmc   +1 more source

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