Results 191 to 200 of about 52,334 (267)

Plasmin-mediated proteolysis of von Willebrand factor in patients with acute and chronic liver disease. [PDF]

Res Pract Thromb Haemost
El Otmani H, Stamouli M, Adelmeijer J, Bernal W, Maas C, Patel VC, Lisman T.   +6 more
europepmc   +1 more source

Haemophilia A in a Female German Shepherd With Homozygosity for the FVIII p.C567Y Variant in Exon 11 of the F8 Gene

Animal Genetics, Volume 57, Issue 4, August 2026.
ABSTRACT Haemophilia A is an extremely rare disorder in females, as the causative F8 gene is located on the X chromosome. Female carriers, also known as ‘conductors,’ are typically heterozygous and therefore do not show clinical signs of the disease. However, in mild forms of haemophilia A, affected males may survive and mate.
Bertram Brenig, Sabrina Pach
wiley   +1 more source

The Role of von Willebrand Factor in the Pathogenesis of C3 Glomerulopathy. [PDF]

Kidney Int Rep
Hua Z, Chen Y, Han S, Yu X, Tan Y, Yu F, Chen M, Zhao M.   +7 more
europepmc   +1 more source

Discovery of VEGFR‐2 Inhibitors From Leonurus japonicus via Integrated Genetic Authentication, Molecular Networking, and In Silico Analysis

Archiv der Pharmazie, Volume 359, Issue 8, August 2026.
Genetic authentication of Leonurus japonicus was confirmed using ITS sequencing. UHPLC‐MS/MS‐GNPS analysis and isolation led to a new labdane diterpenoid (1) and known compounds (2–6), with anti‐angiogenic activity validated by EPC assays and VEGFR‐2 docking studies.
Thiyagarajan Raviraj, Chen‐Lin Yu, Aekkhaluck Intharuksa, Shang‐Chih Lai, Vidya Febrasca Tenderly, Yen Chi Loo, Pin‐Wei Chen, Shih‐Wei Wang, Kartiko Arif Purnomo, Soundar Rajan Kulandhaivel, Sedin Renadi, Stephen Lirio, Yuan‐Bin Cheng, Yu‐Liang Yang, Tsong‐Long Hwang, Fang‐Rong Chang, Michal Korinek   +16 more
wiley   +1 more source

Comparison of Thrombocytopenia and Splenomegaly in Locally Advanced Rectal Cancer Patients Receiving Total Neoadjuvant Therapy With and Without Immunotherapy

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Background Thrombocytopenia is a common toxicity of oxaliplatin‐based chemotherapy and may be linked to hepatic sinusoidal obstruction and splenic enlargement. In the TORCH trial, adding PD‐1 blockade to an oxaliplatin‐containing total neoadjuvant therapy (TNT) regimen improved tumor response in patients with locally advanced rectal cancer ...
Shuwen Li, Mingxu Yan, Qiong Ma, Yiqun Sun, Zhen Zhang, Lijun Shen, Juefeng Wan, Hui Zhang, Ruiyan Wu, Fan Xia, Yaqi Wang   +10 more
wiley   +1 more source

Associations of plasma von Willebrand Factor levels with cognitive decline and neurodegeneration in older adults without dementia. [PDF]

Front Aging Neurosci
Fu P, Hu M.
europepmc   +1 more source

A Therapeutic Dilemma: Catastrophic ST‐Elevation Myocardial Infarction Following Antiplatelet Therapy Interruption in a Patient With JAK2‐Positive Polycythemia Vera

Clinical Case Reports, Volume 14, Issue 8, August 2026.
Premature interruption of dual antiplatelet therapy in a patient with polycythemia vera and clinically suspected acquired von Willebrand syndrome triggered catastrophic recurrent stent thrombosis, whereas perioperative bridging with eptifibatide enabled safe surgery. ABSTRACT Polycythemia vera is associated with a thrombotic–hemorrhagic paradox.
Behrouz zarei, Amirhossein Rezaei Latifi, Mohammad Salari   +2 more
wiley   +1 more source

Altered DNA methylation of the ABO gene is associated with differential plasma levels of von willebrand factor and E-selectin. [PDF]

Transfusion
Lou T, Sugrue JA, Patin E, Milieu Intérieur Consortium, Quintana-Murci L, Duffy D, O'Farrelly C.   +6 more
europepmc   +1 more source

Delayed Recognition of Thrombotic Thrombocytopenic Purpura Following Platelet Transfusion: A Clinical Pitfall

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Thrombotic thrombocytopenic purpura (TTP) is a rare, life‐threatening thrombotic microangiopathy caused by severe ADAMTS13 deficiency, usually due to autoantibody‐mediated inhibition. Its presentation is heterogeneous and often lacks the classic pentad, leading to diagnostic delays. Neurological symptoms may predominate, masking the underlying
Abdulrahman Al‐Dawoudi, Mujahed Dalain, Daniil Varlamov, Shaghaf Alhallak, Dāvis Freimanis   +4 more
wiley   +1 more source