Results 201 to 210 of about 102,475 (311)

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 18, 15 May 2026.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu   +10 more
wiley   +1 more source

Activated Platelet–Released Heat Shock Protein 90α Triggers Autophagy‐Dependent Neutrophil Extracellular Trap Formation and Amplifies Sepsis

open access: yesAdvanced Science, Volume 13, Issue 25, 4 May 2026.
HSP90α is significantly upregulated in platelets from sepsis patients, with its origin from megakaryocyte‐derived trafficking. Furthermore, activated platelets secrete HSP90α into the extracellular space in both free and exosome‐associated forms. Finally, extracellular HSP90α directly engages TLR4 on neutrophils to induce autophagy, leading to NET ...
Chengbo Wang   +17 more
wiley   +1 more source

Publisher Correction to: Identification of a von Willebrand factor type A protein affecting both grain and flag leaf morphologies in wheat. [PDF]

open access: yesSci China Life Sci
Zhou C   +13 more
europepmc   +1 more source

Clot Composition Profiling in Large Vessel Occlusion Stroke Via Radiomics

open access: yesAnnals of Neurology, Volume 99, Issue 5, Page 1179-1188, May 2026.
Objective Clot composition may offer insights into the mechanism of ischemic stroke. Radiomics, a noninvasive imaging technique, enables tissue characterization through radiomic features (RFs). We aimed to evaluate clot composition using radiomics on non‐contrast computed tomography (NCCT).
Andres Gudino   +23 more
wiley   +1 more source

Preoperative Biomarker Panel With Fibrinogen, FVIII, and CA 19–9 as a Tool for Prognostic Evaluation in Neoadjuvant‐Treated Pancreatic Ductal Adenocarcinoma

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background Pancreatic ductal adenocarcinoma (PDAC) is highly thrombogenic and lethal, with rising incidence. Combining carbohydrate antigen (CA) 19–9, fibrinogen, coagulation factor VIII (FVIII), albumin, and alkaline phosphatase (ALP) as a diagnostic panel improves diagnostics.
Nora Mattila   +4 more
wiley   +1 more source

Biologics and Drug‐Induced Immunogenicity: A Case Report of Acquired Hemophilia A Presenting After Immunotherapy

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Acquired hemophilia A is a rare, potentially life‐threatening bleeding disorder caused by autoantibody inhibitors to coagulation factor VIII. We report the case of an 87‐year‐old female who presented with symptomatic bleeding and was subsequently diagnosed with acquired hemophilia A.
Kevin A. Murgas   +4 more
wiley   +1 more source

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