Results 221 to 230 of about 52,208 (254)

Von Willebrand factor and fibrinogen

Current Opinion in Cell Biology, 1993
Progress in understanding the structure and function of von Willebrand factor and fibrinogen has provided new insights into the mechanisms of hemostasis and thrombosis. This, in turn, has generated concepts that may become applicable to the diagnosis and treatment of occlusive vascular diseases and bleeding disorders, both congenital and acquired.
openaire   +2 more sources

Thrombosis and von Willebrand Factor

2015
One of the key players in both hemostasis and thrombosis is von Willebrand factor (vWF), which demonstrates a duality between these two processes. Thrombus is structured by numerous elements, including endothelial cells, platelets, plasma proteins and shear stress alteration.
openaire   +2 more sources

The von Willebrand Factor Gene and Genetics of von Willebrand's Disease

Mayo Clinic Proceedings, 1991
The von Willebrand factor (vWF) gene spans 178 kilobases in the human genome, is interrupted by 51 introns, and has been localized to human chromosome 12p12----12pter. In addition, a pseudogene that duplicates the midportion of the vWF gene has been identified on chromosome 22.
openaire   +2 more sources

Recombinant von Willebrand Factor

Thrombosis and Haemostasis, 1997
H P, Schwarz, P L, Turecek, L, Pichler, A, Mitterer, W, Mundt, F, Dorner, J, Roussi, L, Drouet   +7 more
openaire   +2 more sources

Assembly Mechanism of Mucin and von Willebrand Factor Polymers

Cell, 2020
Gabriel Javitt, Lev Khmelnitsky, Lavi S Bigman   +2 more
exaly  

Inhibition of Willebrand factor in von Willebrand disease

Thrombosis Research, 1979
S, Maragall, R, Castillo, A, Ordinas, F, Liendo, M, Rodríguez   +4 more
openaire   +2 more sources

Von Willebrand factor and von Willebrand disease

Von Willebrand disease (vWD) is an autosomally inherited bleeding disorder caused by a deficiency or abnormality of von Willebrand factor (vWF). vWF is a large multimeric glycoprotein that mediates platelet adhesion at the site of vessel injury. Also, it protects factor VIII from proteolytic degradation in the circulation. vWD has a prevalence of about
openaire   +1 more source

Factor-VIII/Von Willebrand factor/Von Willebrand factor

Reactions Weekly, 2015
openaire   +1 more source

First-in-Human Evaluation of Anti–von Willebrand Factor Therapeutic Aptamer ARC1779 in Healthy Volunteers

Circulation, 2007
James C Gilbert, Robert G Schaub
exaly  

Update on the pathophysiology and classification of von Willebrand disease: a report of the Subcommittee on von Willebrand Factor

Journal of Thrombosis and Haemostasis, 2006
J E Sadler, Jeroen Eikenboom, E J Favaloro   +2 more
exaly