Results 231 to 240 of about 52,334 (267)

von Willebrand Factor, von Willebrand Factor-Cleaving Protease, and Shear Stress

Cardiovascular & Hematological Agents in Medicinal Chemistry, 2007
von Willebrand factor (VWF) is a multimeric plasma glycoprotein (GP) involved in platelet adhesion at the site of vascular damage, which acts as a bridge between the injured subendothelium and the platelet receptors. The multimeric structure of VWF allows it to support multiple interactions with platelets and endothelial components under high shear ...
P, Perutelli, A C, Molinari
openaire   +2 more sources

von Willebrand Factor and Aging

Seminars in Thrombosis and Hemostasis, 2014
von Willebrand factor (VWF) plays critical roles in initiating primary hemostasis and extending the half-life of coagulation factor VIII in circulation. VWF levels increase with age and elevated levels are associated with an increased risk of venous thromboembolism and cardiovascular disease (CVD).
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Von Willebrand factor and fibrinogen

Current Opinion in Cell Biology, 1993
Progress in understanding the structure and function of von Willebrand factor and fibrinogen has provided new insights into the mechanisms of hemostasis and thrombosis. This, in turn, has generated concepts that may become applicable to the diagnosis and treatment of occlusive vascular diseases and bleeding disorders, both congenital and acquired.
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Thrombosis and von Willebrand Factor

2015
One of the key players in both hemostasis and thrombosis is von Willebrand factor (vWF), which demonstrates a duality between these two processes. Thrombus is structured by numerous elements, including endothelial cells, platelets, plasma proteins and shear stress alteration.
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The von Willebrand Factor Gene and Genetics of von Willebrand's Disease

Mayo Clinic Proceedings, 1991
The von Willebrand factor (vWF) gene spans 178 kilobases in the human genome, is interrupted by 51 introns, and has been localized to human chromosome 12p12----12pter. In addition, a pseudogene that duplicates the midportion of the vWF gene has been identified on chromosome 22.
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Recombinant von Willebrand Factor

Thrombosis and Haemostasis, 1997
H P, Schwarz, P L, Turecek, L, Pichler, A, Mitterer, W, Mundt, F, Dorner, J, Roussi, L, Drouet   +7 more
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Inhibition of Willebrand factor in von Willebrand disease

Thrombosis Research, 1979
S, Maragall, R, Castillo, A, Ordinas, F, Liendo, M, Rodríguez   +4 more
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Factor-VIII/Von Willebrand factor/Von Willebrand factor

Reactions Weekly, 2015
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Assembly Mechanism of Mucin and von Willebrand Factor Polymers

Cell, 2020
Nadav Elad, Deborah Fass, Lev Khmelnitsky   +2 more
exaly  

Von Willebrand factor and von Willebrand disease

Von Willebrand disease (vWD) is an autosomally inherited bleeding disorder caused by a deficiency or abnormality of von Willebrand factor (vWF). vWF is a large multimeric glycoprotein that mediates platelet adhesion at the site of vessel injury. Also, it protects factor VIII from proteolytic degradation in the circulation. vWD has a prevalence of about
openaire   +1 more source