Results 261 to 270 of about 219,337 (367)

Impaired nitric oxide‐dependent endothelial function in young male individuals with obesity before the onset of symptoms and complications

Experimental Physiology, EarlyView.
Abstract Endothelial dysfunction drives obesity‐related complications. Doppler ultrasound measurement of blood flow during 1‐min passive leg movements (PLM) is a valuable non‐invasive tool for assessing endothelial function and nitric oxide (NO)‐mediated vasodilation.
Lucrezia Zuccarelli, Giovanni Baldassarre, Adele Bondesan, Diana Caroli, Roberta De Micheli, Gabriella Tringali, Thomas Favaretto, Joanna Suraj‐Prazmowska, Anna Kurpinska, Joanna Majerczak, Stefan Chlopicki, Jerzy A. Zoladz, Alessandro Sartorio, Bruno Grassi   +13 more
wiley   +1 more source

Key residues regulating von Willebrand factor A1/A2 interactions: insights from molecular dynamics simulations and experimental validation. [PDF]

Res Pract Thromb Haemost
Fang J, Wu Z, Yang J, Huang Y, Liu A, Lin J.   +5 more
europepmc   +1 more source

Von Willebrand syndrome induced by a Bothrops venom factor: bioassay for venom coagglutinin.

, 1981
K. M. Brinkhous, D S Barnes, J Y Potter, Marjorie S. Read   +3 more
openalex   +2 more sources

The RhoA guanine exchange factor ABR: a glucose‐sensitive mediator of actin reorganization in feto‐placental arterial endothelial cells altered by gestational diabetes mellitus

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of proposed relationship between hyperglycaemia, gestational diabetes mellitus (GDM), active BCR‐related (ABR), RhoA and actin organization of feto‐placental arterial endothelial cells (fpEC). Hyperglycaemia upregulates ABR, which in turn increases RhoA activation.
Silvija Tokic, Boris Novakovic, Barbara Leopold‐Posch, Magdalena Mühlberger, Denise Hoch, Jelena Lögl, Eva M. Bernhart, Richard Saffery, Gernot Desoye, Ursula Hiden   +9 more
wiley   +1 more source

Altered DNA methylation of the ABO gene is associated with differential plasma levels of von willebrand factor and E-selectin. [PDF]

Transfusion
Lou T, Sugrue JA, Patin E, Milieu Intérieur Consortium, Quintana-Murci L, Duffy D, O'Farrelly C.   +6 more
europepmc   +1 more source

Mobilization mechanism of von Willebrand Factor (VIII VWF) from the platelets and its significance in Thrombogenesis

, 1978
Minako KAJIKAWA, Yoshinori TAKETOMI, Kingo Fujimura, Akihiro Ihara, Naosada WAKASA, Atsushi Kuramoto   +5 more
openalex   +2 more sources

Continuity of care in immune thrombotic thrombocytopenic purpura (iTTP): A visual roadmap for survivorship beyond acute management

Transfusion, EarlyView.
Jesse Qiao, Minh‐Ha Tran, Jennifer Jones, Sierra Simmons   +3 more
wiley   +1 more source

ROC‐325 Attenuates Hypoxia‐Induced Pulmonary Hypertension Through Dual Inhibition of Autophagy and Hypoxia‐Inducible Factor 2α Signaling

MedComm – Future Medicine, Volume 5, Issue 1, March 2026.
In hypoxia‐induced pulmonary hypertension, endothelial HIF‐2α accumulation and autophagic activation drive vascular remodeling. We demonstrate that the novel lysosomal inhibitor ROC‐325 simultaneously attenuates this pathogenic autophagy and promotes HIF‐2α degradation.
Changlei Bao, Shuxin Liang, Dingyuan Liu, Xingting Wang, Dan Bai, Chuangjia Huang, Hanliang Sun, Zi Yang, Bitao Wu, Zixuan Chen, Jieyi Feng, Zinan Luo, Jintao Long, Jinsheng Zhu, June Bai, Li Zhang, Aiai Chu, Caojin Zhang, Haiyang Tang   +18 more
wiley   +1 more source

Deep molecular modeling and mechanistic insights into type 2A von Willebrand disease with von Willebrand factor A2 domain mutations. [PDF]

Res Pract Thromb Haemost
Seidizadeh O, Mollica L, Giana D, Baronciani L, Colpani P, Sicuro L, Cairo A, Peyvandi F.   +7 more
europepmc   +1 more source

Hemostatic efficacy, safety, and pharmacokinetics of a recombinant von Willebrand factor in severe von Willebrand disease.

Blood, 2015
J. Gill, G. Castaman, J. Windyga, P. Kouides, M. Ragni, F. Leebeek, Ortrun Obermann-Slupetzky, M. Chapman, S. Fritsch, B. Pavlova, I. Presch, B. Ewenstein   +11 more
semanticscholar   +1 more source