Results 321 to 330 of about 214,027 (378)

DiPTH‐Cystine and PTH‐Cysteine in Disulfide Bond Analysis Using Automated Edman Degradation

Journal of Peptide Science, Volume 31, Issue 10, October 2025.
The mystery of PTH‐cysteine and diPTH‐cystine in the analysis of disulfide bonds is solved. Both derivatives were synthesized and applied to Edman sequencing. A time‐efficient combined workflow applying Edman and MS/MS sequencing for a comprehensive analysis of the complex disulfide connectivity in peptides and proteins was developed.
Toni Kühl, Yomnah Y. Elsayed, Alexander Terekhov, Diana Imhof   +3 more
wiley   +1 more source

R1205H (Vicenza) causes conformational changes in the von Willebrand factor D'D3 domains and enhances von Willebrand factor binding to clearance receptors LRP1 and SR-AI. [PDF]

J Thromb Haemost
Atiq F, Rawley O, O'Sullivan JM, Özbil M, Doherty D, Cooke N, Terraube V, Chion A, Amin A, Hulshof AM, Baci B, Byrne C, Aburawi HE, Lillicrap D, O'Donnell JS.   +14 more
europepmc   +1 more source

Quantitative Systems Pharmacology Modeling of Platelet Responses to Recombinant ADAMTS13 in Patients With Congenital Thrombotic Thrombocytopenic Purpura

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 10, Page 1575-1586, October 2025.
ABSTRACT Congenital thrombotic thrombocytopenic purpura (cTTP) is an ultra‐rare, life‐threatening thrombotic microangiopathy caused by a severe inherited deficiency of ADAMTS13, a von Willebrand factor (VWF) cleaving enzyme. Inadequate clinical endpoint data often make it challenging to statistically power clinical trials in ultra‐rare diseases ...
Cameron McBride, Jiaolong Jiang, Zhiwei Zhang, John Tolsma, Parth Patwari, Björn Mellgård, Majid Vakilynejad, Indranil Bhattacharya, Andy Z. X. Zhu   +8 more
wiley   +1 more source

A fully magnetically levitated left ventricular assist device — final report [PDF]

, 2019
Ewald, G.A., Itoh, A.
core   +1 more source

Wind‐Driven Mid‐Depth Pacific Cooling in a Dynamically Consistent Ocean State Estimate

Journal of Geophysical Research: Oceans, Volume 130, Issue 10, October 2025.
Abstract A comparison of 19th century HMS Challenger hydrography with modern observations indicated the mid‐depth Pacific has cooled at a rate of 5±3 $5\pm 3$ centikelvin (cK, 1cK=0.01kelvin $1\,\mathrm{cK}=0.01\,\mathrm{kelvin}$) per century and could be explained as a slow ongoing adjustment to the Little Ice Age. The historical hydrographic data was
Anthony Meza, Geoffrey Gebbie
wiley   +1 more source

Plasma proteomics in patients with von Willebrand disease and hemophilia A highlights von Willebrand factor as main determinant of response to desmopressin treatment. [PDF]

Res Pract Thromb Haemost
Alferez JDC, Smit ER, Meijer AB, Fijnvandraat K, Kruip MJHA, van Duijl TT, van den Biggelaar M.   +6 more
europepmc   +1 more source

Refractory anaemia in a patient with end‐stage heart failure secondary to aortic stenosis

ESC Heart Failure, Volume 12, Issue 5, Page 3766-3770, October 2025.
Jiayu Liang, Suxin Luo, Bi Huang
wiley   +1 more source

Survey of functional Mendelian variants in New Zealand Huntaway and Heading dog breeds

Animal Genetics, Volume 56, Issue 5, October 2025.
Abstract New Zealand (NZ) Huntaway and Heading dogs are working breeds that play active roles on farms across NZ. While these breeds are common in NZ, they are not well‐known elsewhere, and little is understood about their genetic make‐up. Here, we used whole genome sequencing to provide a comprehensive genomic view of 249 working dogs. As first use of
Florence Smith, Thomas Lopdell, Melissa Stephen, Millicent Henry, Keren Dittmer, Hayley Hunt, Nick Sneddon, Liam Williams, Jack Rolfe, Dorian Garrick, Mathew D. Littlejohn   +10 more
wiley   +1 more source

Plasma von Willebrand factor levels in patients with cancer: A meta‑analysis. [PDF]

Oncol Lett
Wang X, Zhang X, Zhang C, Qi L, Liu J.
europepmc   +1 more source

Medical haematology trial eligibility and the Duffy null‐associated neutrophil count: A cross‐sectional study

HemaSphere, Volume 9, Issue 10, October 2025.
Olga Tsiamita, Laura Aiken, Mohsin Badat, Gill Lowe, Funmi Oyesanya, Sonia Wolf, Lauren E. Merz, Andrew Hantel, Stephen P. Hibbs   +8 more
wiley   +1 more source