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von Willebrand factor and von Willebrand disease.
[Rinsho ketsueki] The Japanese journal of clinical hematology, 2017von Willebrand factor (VWF) has two major roles in hemostasis, as a form of molecular glue which functions in platelet plug formation and as a protective transporter for coagulation factor VIII (FVIII). VWF shows a multimeric chain structure composed of 270 kDa subunits containing binding domains for FVIII, platelet and collagens. Biosynthesis, storage,
Taei, Matsui, Jiharu, Hamako
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Recombinant von Willebrand Factor
Thrombosis and Haemostasis, 1997H P, Schwarz +7 more
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Von Willebrand factor and von Willebrand disease
2005Von Willebrand disease (vWD) is an autosomally inherited bleeding disorder caused by a deficiency or abnormality of von Willebrand factor (vWF). vWF is a large multimeric glycoprotein that mediates platelet adhesion at the site of vessel injury. Also, it protects factor VIII from proteolytic degradation in the circulation. vWD has a prevalence of about
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Factor-VIII/Von Willebrand factor/Von Willebrand factor
Reactions Weekly, 2015openaire +1 more source
A biophysical view on von Willebrand factor activation
Journal of Cellular Physiology, 2018Achim Löf, Jochen P. Müller, M. Brehm
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Thrombosis and von Willebrand Factor.
Advances in Experimental Medicine and Biology, 2016M. Shahidi
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