Results 31 to 40 of about 8,401,904 (201)
Clinical Pediatric Hematology-Oncology, 2021 von Willebrand disease (VWD) is the most common hereditary bleeding disorder. The treatment of VWD consists mainly of desmopressin and plasma-derived von Willebrand factor (pd-VWF) concentrate.
Seoin Kim, Young Shil Park
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Clearance of von Willebrand factor [PDF]
Journal of Thrombosis and Haemostasis, 2013 Quantitative deficiencies in von Willebrand factor (VWF) are associated with abnormal hemostasis that can manifest in bleeding or thrombotic complications. Consequently, many studies have endeavored to elucidate the mechanisms underlying the regulation of VWF plasma levels. This review focuses on the role of VWF clearance pathways.
C, Casari +4 more
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Haematologica, 2017 Factor VIII C-domains are believed to have specific functions in cofactor activity and in interactions with von Willebrand factor. We have previously shown that factor VIII is co-targeted with von Willebrand factor to the Weibel-Palade bodies in blood ...
Eduard H.T.M. Ebberink +7 more
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The role of von Willebrand factor in determining the risk of ischemic stroke in Hawler city: a case-control study [PDF]
Zanco Journal of Medical Sciences, 2018 Background and objective: Ischemic stroke is classically characterized as a neurological deficit attributed to an acute focal injury of the central nervous system by a vascular cause, it occurs as a result of obstruction by a blood clot (thrombus) or ...
Sazgar Anwar Hameed, Salar Adnan Ahmed
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Zebrafish von Willebrand factor [PDF]
Blood Cells, Molecules, and Diseases, 2010 von Willebrand factor (vWF) is a large protein involved in primary hemostasis. A dysfunction in this protein or an insufficient production of the protein leads to improper platelet adhesion/aggregation, resulting in a bleeding phenotype known as von Willebrand disease (vWD).
Maira, Carrillo +4 more
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Научно-практическая ревматология, 2004 Objective. To determine the importance of von Willebrand factor antigen as marker of endotheliae damage at the patients with systemic lupus erythematosus (SLE). Material and methods. 30 women from authentic SLE by criteria ACR, in the age of 20-45 years,
M E Zapryagaeva, E S Mach, A A Baranov
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Successful Aortic Aneurysm Repair in a Woman with Severe von Willebrand (Type 3) Disease
Case Reports in Hematology, 2015 von Willebrand disease type 3 (VWD3) is a rare but the most severe form of von Willebrand disease; it is due to almost complete lack of von Willebrand factor activity (VWF:RCo).
Victoria Campbell +3 more
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Haematologica, 2013 Initial platelet arrest at the exposed arterial vessel wall is mediated through glycoprotein Ibα binding to the A1 domain of von Willebrand factor. This interaction occurs at sites of elevated shear force, and strengthens upon increasing hydrodynamic ...
Eelo Gitz +8 more
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Ibrutinib effect in acquired von Willebrand syndrome secondary to Waldenström macroglobulinemia
Therapeutic Advances in Hematology, 2021 The pathological increase of clonal IgM in Waldenström macroglobulinemia can be associated with acquired von Willebrand syndrome and can be a major risk of bleeding symptoms in this subgroup of patients with Waldenström macroglobulinemia.
María Poza +6 more
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Medicina, 2023 Acquired von Willebrand factor deficiency has been described in patients with aortic valve stenosis due to high shear forces developed during passage through the narrowed valve orifice, which determines structural changes in this molecule.
Andrei Emanuel Grigorescu +3 more
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