Results 51 to 60 of about 102,475 (311)

Mechanically Spatio‐Chimeric Fibrin Assembly Enables Vascular‐Integrated Muscle Reconstruction for Volumetric Muscle Loss Repair

open access: yesAdvanced Materials, EarlyView.
SPARC (spatio‐chimeric, plasma‐based, anisotropic, and shear‐responsive construct) that integrates myogenic and vascular microenvironments within a single construct. The dual‐modulus matrix directs aligned myotube formation and endothelial network development, enabling a vascularized muscle implant that seamlessly anastomoses with host tissue and ...
Su Hyun Jung   +6 more
wiley   +1 more source

Nitric Oxide and Von Willebrand Factor Levels as Markers of Endothelial Dysfunction in Liver Cirrhosis [PDF]

open access: yes, 2002
Introduction: A number of investigators have shown that endothelial dysfunction in liver cirrhosis can be indicated by increased levels of nitric oxide (NO) and von Willebrand factor (vWF). The cause of this increase is still unclear. It is believe to be
Ginting, S. (Suara)   +4 more
core  

Desmopressin in moderate hemophilia a patients: A treatment worth considering [PDF]

open access: yes, 2018
Desmopressin increases endogenous factor VIII levels in hemophilia A. Large inter-individual variation in the response to desmopressin is observed.
Beckers, E.   +12 more
core   +4 more sources

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

open access: yesAdvanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim   +6 more
wiley   +1 more source

Cadmium regulates von Willebrand factor and occludin expression in glomerular endothelial cells of mice in a TNF-α-dependent manner

open access: yesRenal Failure, 2019
Background: Cadmium (Cd) is an environmental pollutant that leads to nephrotoxicity. However, the mechanisms of Cd-induced glomerular injury have not been fully clarified. Von Willebrand factor (vWF) and occludin are important endothelial cell markers in
Zongguo Sun, Qi Xie, Jie Pan, Na Niu
doaj   +1 more source

Az érfal trombogenitása és annak szabályozása = Vessel wall thrombogenicity and its regulation [PDF]

open access: yes, 2008
Fiziológiás hemosztázis ill. artériás trombózis keletkezésekor a trombociták a gyorsan áramló vérből von Willebrand faktoron keresztül tapadnak ki az érfalban lévő kollagénhez. Az érfal mátrix komponenseit vizsgálva megállapítottuk, hogy a media rétegből
Gombás, Judit   +2 more
core  

Von Willebrand factor, angiodysplasia and angiogenesis [PDF]

open access: yes, 2013
The large multimeric glycoprotein Von Willebrand factor (VWF) is best known for its role in haemostasis; however in recent years other functions of VWF have been identified, indicating that this protein is involved in multiple vascular processes.
Laffan, MA, Randi, AM, Starke, RD
core   +2 more sources

Von Willebrand factor revisited

open access: yesJournal of Interventional Cardiology, 2017
Degenerative aortic valve stenosis is the most common valvular heart disease seen in developed countries. Since the implementation of transcatheter aortic valve replacement, there has been a surge of efforts to improve procedural technique as well as reduce mortality.
Senan J. Yasar   +3 more
openaire   +2 more sources

Of von Willebrand factor and platelets [PDF]

open access: yesCellular and Molecular Life Sciences, 2014
Hemostasis and pathological thrombus formation are dynamic processes that require multiple adhesive receptor-ligand interactions, with blood platelets at the heart of such events. Many studies have contributed to shed light on the importance of von Willebrand factor (VWF) interaction with its platelet receptors, glycoprotein (GP) Ib-IX-V and αIIbβ3 ...
Bryckaert, Marijke   +3 more
openaire   +2 more sources

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

open access: yesAdvanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee   +11 more
wiley   +1 more source

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