Results 51 to 60 of about 8,401,904 (201)

The relationship between ADAMTS13 genotype and phenotype in congenital thrombotic thrombocytopenic purpura and characterisation of ADAMTS13 mutants [PDF]

, 2015
Congenital thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathy, usually involving ADAMTS13 gene defects. ADAMTS13 processes the multimeric plasma glycoprotein Von Willebrand factor making it less reactive to platelets.
Underwood, MI
core  

Value of Von Willebrand Factor as a Predictor for Osteoporosis Development in Women with Hypothyroidism

Mìžnarodnij Endokrinologìčnij Žurnal, 2015
The paper presents the study of the value of von Willebrand factor as a marker of endothelial dysfunction for osteoporosis development and for prediction of risk of its formation in women with hypothyroidism. Postmenopausal women with hypothyroidism have
I.V. Pankiv
doaj   +1 more source

Erythrocytes and von Willebrand factor in venous thrombosis [PDF]

, 2018
Venous thromboembolism represents the third leading vascular disease after myocardial infarction and stroke. Erythrocytes, the most abundant cells in venous thrombi, were thought to be innocent bystanders that become tangled up in the fibrin mesh of ...
Smeets, M.W.J.
core   +7 more sources

The epitope of the antibody used in the REAADS VWF activity assay is quaternary

Thrombosis Journal
The REAADS VWF activity assay is often assumed to be specific for the A1 domain, the portion of VWF that binds platelet GPIbα. We tested this assay on the A1A2A3 region of VWF with each domain expressed independently of one another and together in ...
Alexander Tischer, Laurie Moon-Tasson, Matthew Auton   +2 more
doaj   +1 more source

von Willebrand Factor (VWF) Inhibitors in Two Brothers with von Willebrand Disease: A Case Report

TH Open
The development of inhibitors to von Willebrand factor (VWF) is a rare but potentially serious complication of VWF replacement therapy in patients with von Willebrand disease (VWD).
Claudia Djambas Khayat, Anna Pavlova, Sylvia Werner, Sigurd Knaub, Robert F. Sidonio   +4 more
doaj   +1 more source

Differential cargo mobilisation within Weibel-Palade bodies after transient fusion with the plasma membrane. [PDF]

, 2014
Inflammatory chemokines can be selectively released from Weibel-Palade bodies (WPBs) during kiss-and-run exocytosis. Such selectivity may arise from molecular size filtering by the fusion pore, however differential intra-WPB cargo re-mobilisation ...
Knipe, Laura, Tom Carter (196826), Carter, T, Laura Knipe (196817), Hannah, MJ, Kiskin, Nikolai I, Kiskin, NI, Nikolai I Kiskin, Matthew J. Hannah (196824), Matthew J Hannah, Babich, Victor, Nikolai I. Kiskin (631240), Victor Babich, Knipe, L, Tom Carter, Victor Babich (631241), Laura Knipe, Carter, Tom, Babich, V, Hannah, Matthew J   +19 more
core   +1 more source

DISCOVERY OF TYPE 3 VON WILLEBRAND DISEASE IN A COHORT OF PATIENTS WITH SUSPECTED HEMOPHILIA A IN CÔTE D’IVOIRE

Mediterranean Journal of Hematology and Infectious Diseases, 2020
Aim : Type 3 von Willebrand disease (VWD) is the most severe form of VWD, characterized by a near-total absence of von Willebrand factor (vWF) leading to a huge deficiency in plasmatic factor VIII (FVIII). VWD may be confused with hemophilia A, sometimes
Adia Eusèbe Adjambri, Sylvie Bouvier, Roseline N'guessan, Emma N’draman-Donou, Mireille Yayo-Ayé, Marie-France Meledje, Missa Louis Adjé, Duni Sawadogo   +7 more
doaj   +1 more source

Factor VIII/von Willebrand factor binding to von Willebrand's disease platelets [PDF]

Blood, 1982
A form of von Willebrand's disease has been described with enhanced ristocetin-induced platelet aggregation and anodal migration of the factor VIII/von Willebrand factor protein (type IIb). We studied two families with this form of von Willebrand's disease and macrothrombocytopenia.
H R, Gralnick, S B, Williams, B C, Shafer, L, Corash   +3 more
openaire   +3 more sources

Management of von Willebrand disease with factor VIII/von Willebrand factor concentrates: results from current studies and surveys

, 2005
Until the mid 1980s, cryoprecipitate had been the mainstay of treatment of patients with von Willebrand disease (VWD) who were unresponsive to desmopressin.
A.B. Federici
core   +1 more source

Historical perspective on von Willebrand disease

In 1926, the Finnish physician Erik Adolf von Willebrand first described an inherited bleeding disorder with features that suggested that this disease was distinct from classic hemophilia and other bleeding disorders.
Berntorp, Erik E.,, Blombäck, Margareta,, Lund University.   +2 more
core   +1 more source